{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:07:41Z","timestamp":1790489261639,"version":"4.1.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T00:00:00Z","timestamp":1528070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Telemed Telecare"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Tele-monitoring (TM) has proved effective in the home management of adult ventilator-dependent neuromuscular disease (NMD) patients. We aimed to evaluate a 2-year longitudinal multicentre TM trial designed for young ventilated NMD patients in terms of feasibility, home management of exacerbations and caregivers\u2019 burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The TM trial protocol included patients\u2019 weekly scheduled overnight home-recording of SpO\n                      <jats:sub>2<\/jats:sub>\n                      , heart rate and ventilation and their transmission to each TM centre the following morning. Overnight data were reviewed by non-physicians and calls to families made to assess clinical condition. If clinical conditions (assessed by a scoring system) or overnight parameters worsened, either unscheduled transmissions or calls were activated and managed by non-physicians or medical team according to severity. Hospitalisations were compared with those of TM patients prior to TM start and with those of age-disease-severity-matched controls. Scores from the Caregiver Burden Inventory (CBI) questionnaire pre- and post-TM were compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty-eight patients were enrolled, 30 males, median age 16.4 years (interquartile range (IQR) 8.9\u201322.1), median ventilation\/day 10.5\u2009h (IQR 8\u201316). Exacerbations in TM patients did not differ (59 versus 53; p\u2009=\u20090.15) from controls. Hospitalisations were significantly reduced in TM patients when compared with those prior to TM (11 versus 24, p\u2009=\u20090.04) and to controls (11 versus 21, p\u2009=\u20090.03). Median hospitalisation length was significantly lower in TM patients than controls (6 versus 7 days, p\u2009=\u20090.03 ). Caregivers satisfaction was excellent whereas no significant changes in CBI were seen (32.5 versus 35.5, p\u2009=\u20090.06).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>TM was effective in improving the home management of respiratory exacerbations in young ventilated NMD patients and overall well tolerated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1357633x18778479","type":"journal-article","created":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T01:28:01Z","timestamp":1528162081000},"page":"414-424","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":38,"title":["Tele-monitoring in paediatric and young home-ventilated neuromuscular patients: A multicentre case-control trial"],"prefix":"10.1177","volume":"25","author":[{"given":"Federica","family":"Trucco","sequence":"first","affiliation":[{"name":"Paediatric Neurology and Muscle Disease Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Pedemonte","sequence":"additional","affiliation":[{"name":"Paediatric Neurology and Muscle Disease Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Racca","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care Unit, Ospedale SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Falsaperla","sequence":"additional","affiliation":[{"name":"Unit of Paediatrics, Policlinico Vittorio Emanuele, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catia","family":"Romano","sequence":"additional","affiliation":[{"name":"Unit of Paediatrics, Policlinico Vittorio Emanuele, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Wenzel","sequence":"additional","affiliation":[{"name":"Unit of Paediatrics, Policlinico Vittorio Emanuele, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"D\u2019Agostino","sequence":"additional","affiliation":[{"name":"Paediatric Neurology and Muscle Disease Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Pistorio","sequence":"additional","affiliation":[{"name":"Epidemiology and Biostatistics Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Tacchetti","sequence":"additional","affiliation":[{"name":"Paediatric Neurology and Muscle Disease Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Bella","sequence":"additional","affiliation":[{"name":"Paediatric Intensive Care Unit, Ospedale SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Bruno","sequence":"additional","affiliation":[{"name":"Centre of Myology and Neurodegenerative Disorders, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Minetti","sequence":"additional","affiliation":[{"name":"Paediatric Neurology and Muscle Disease Unit, Istituto Giannina Gaslini, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,4]]},"reference":[{"key":"bibr1-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(02)00140-2"},{"key":"bibr2-1357633X18778479","first-page":"892","volume":"77","author":"Racca F","year":"2011","journal-title":"Minerva Anestesiol"},{"key":"bibr3-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2504001"},{"key":"bibr4-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e318232883a"},{"key":"bibr5-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02501"},{"key":"bibr6-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-2278"},{"key":"bibr7-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00005608"},{"key":"bibr8-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1258\/jtt.2009.090604"},{"key":"bibr9-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.3109\/17483107.2011.652999"},{"key":"bibr10-1357633X18778479","first-page":"51","volume":"49","author":"Garuti G","year":"2013","journal-title":"Eur J Phys Rehabil Med"},{"key":"bibr11-1357633X18778479","first-page":"57","volume":"77","author":"Bertini S","year":"2012","journal-title":"Monaldi Arch Chest Dis"},{"key":"bibr12-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207045"},{"key":"bibr13-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.206680"},{"key":"bibr14-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01721-2015"},{"key":"bibr15-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-200206000-00003"},{"key":"bibr16-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.177832"},{"key":"bibr17-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70272-8"},{"key":"bibr18-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e3181d89760"},{"key":"bibr19-1357633X18778479","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/29.6.798"}],"container-title":["Journal of Telemedicine and Telecare"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1357633X18778479","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1357633X18778479","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1357633X18778479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:12:23Z","timestamp":1777691543000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1357633X18778479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,4]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1177\/1357633X18778479"],"URL":"https:\/\/doi.org\/10.1177\/1357633x18778479","relation":{},"ISSN":["1357-633X","1758-1109"],"issn-type":[{"value":"1357-633X","type":"print"},{"value":"1758-1109","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,4]]}}}