{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:09:11Z","timestamp":1777936151667,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1998,2,1]],"date-time":"1998-02-01T00:00:00Z","timestamp":886291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasc Med"],"published-print":{"date-parts":[[1998,2]]},"abstract":"<jats:p>Whole-body exercise thallium imaging (WBEI) can show abnormalities of leg muscle perfusion in patients with symptomatic peripheral artery disease (PAD). This study compared the exercise distribution of thallium-201 at different levels of the legs in asymptomatic smokers and non-smokers who performed a maximal graded treadmill test. A group of 74 smokers (more than 20 pack-years) with (n = 51) or without coronary artery disease (CAD) (n = 23) were included in group 1 and 64 non-smokers with a low probability of PAD and CAD in group 2. Patients in group 1 were older than the patients in group 2 (58 6 9 versus 48 6 12 years, p &lt;0.0001). Indexes of asymmetry were significantly higher in group 1, at each level of the legs, both in anterior and posterior views (0.001 &lt; p &lt; 0.05), except at thigh level in anterior view. Fractional uptake indexes of thallium-201 were significantly lower in group 1 than in group 2 at calf level (p = 0.0001 in anterior and posterior views) and buttocks (p = 0.006 and p = 0.009 in anterior view only). Interextremity asymmetry was four to six times more frequent at calf level in smokers than in non-smokers. These WBEI abnormalities in smokers are highly suggestive of silent PAD or at least decreased vascular reactivity in clinically uninvolved vessels.<\/jats:p>","DOI":"10.1177\/1358836x9800300104","type":"journal-article","created":{"date-parts":[[2007,1,18]],"date-time":"2007-01-18T20:21:47Z","timestamp":1169151707000},"page":"15-20","source":"Crossref","is-referenced-by-count":7,"title":["Whole-body exercise thallium imaging in smokers"],"prefix":"10.1177","volume":"3","author":[{"given":"Philippe","family":"Tellier","sequence":"first","affiliation":[{"name":"Centre de M\u00e9decine Nucl\u00e9aire de l\u2019Artois (CMNA), Clinique Sainte Catherine, Sainte-Catherine-Les-Arras, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Lecouffe","sequence":"additional","affiliation":[{"name":"Centre de M\u00e9decine Nucl\u00e9aire de l\u2019Artois (CMNA), Clinique Sainte Catherine, Sainte-Catherine-Les-Arras, 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