{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:10:14Z","timestamp":1777936214787,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,9,29]],"date-time":"2009-09-29T00:00:00Z","timestamp":1254182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vasc Med"],"published-print":{"date-parts":[[2010,2]]},"abstract":"<jats:p>Varicose veins (VVs) are associated with lifestyle-limiting symptoms and complications. Patients who fail compression therapy are candidates for more invasive treatments. This study evaluates the efficacy and safety of endovenous foam sclerotherapy (EFS) for the treatment of VVs in a US academic center. We reviewed medical records of a consecutive cohort of patients who underwent EFS over a 2-year period. The primary outcome measure was obliteration of VVs. The secondary outcome measures were symptomatic improvement, ulcer healing, recurrence, and adverse events. A total of 166 patients (217 legs) underwent EFS for pain (81%), pruritis (41%), swelling (17%), ulcerations (17%), thrombophlebitis (14%), and varix rupture (3%). Complete (65%) or near-complete (34%) obliteration was achieved in 215 (99%) legs after one injection. Additional injections achieved complete obliteration in 39 of 53 legs. Ninety-three percent (27\/29) of active ulcers healed or were decreasing in size. Five ulcers and 11 VVs recurred. Common adverse events included pain and hyperpigmentation. Thrombosis, hematoma, skin necrosis, and neurologic events were rare. In conclusion, EFS appears to be a safe and effective outpatient therapy for the treatment of symptomatic and complicated VVs.<\/jats:p>","DOI":"10.1177\/1358863x09106325","type":"journal-article","created":{"date-parts":[[2009,9,29]],"date-time":"2009-09-29T22:00:57Z","timestamp":1254261657000},"page":"27-32","source":"Crossref","is-referenced-by-count":20,"title":["Effectiveness of foam sclerotherapy for the treatment of varicose veins"],"prefix":"10.1177","volume":"15","author":[{"given":"Raha","family":"Nael","sequence":"first","affiliation":[{"name":"Department of Internal Medicine: Cardiovascular Section, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Rathbun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine: Cardiovascular Section, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,9,29]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810204"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra055289"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.72.4.312"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(95)70195-8"},{"issue":"4","key":"atypb5","first-page":"CD004980","author":"Rigby KA","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(44)90202-3"},{"key":"atypb7","first-page":"9","volume":"47","author":"Bergan J.","year":"2006","journal-title":"J Cardiovasc Surg"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2007.07.022"},{"key":"atypb9","first-page":"129","volume":"53","author":"Tessari L.","year":"2000","journal-title":"Phlebologie"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.01.015"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2006.09.005"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5891"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5423"},{"key":"atypb14","first-page":"6","volume":"30","author":"Barrett JM","year":"2004","journal-title":"Dermatol Surg"},{"key":"atypb15","first-page":"11","volume":"28","author":"Frullini A.","year":"2002","journal-title":"Dermatol Surg"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1177\/026835550201700105"},{"key":"atypb17","first-page":"723","volume":"30","author":"Kahle B.","year":"2004","journal-title":"Dermatol Surg"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.06.030"},{"key":"atypb19","first-page":"213","volume":"49","author":"Luebke T.","year":"2008","journal-title":"J Cardiovasc Surg"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1258\/phleb.2007.007073"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2005.09.032"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1097\/00042728-200502000-00001"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30209.x"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.02.062"},{"key":"atypb25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2007.09.006"},{"key":"atypb26","first-page":"1170","volume":"29","author":"Hamel-Desnos C.","year":"2004","journal-title":"Dermatol Surg"}],"container-title":["Vascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1358863X09106325","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1358863X09106325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:23:12Z","timestamp":1777692192000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1358863X09106325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9,29]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["10.1177\/1358863X09106325"],"URL":"https:\/\/doi.org\/10.1177\/1358863x09106325","relation":{},"ISSN":["1358-863X","1477-0377"],"issn-type":[{"value":"1358-863X","type":"print"},{"value":"1477-0377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9,29]]}}}