{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:10:47Z","timestamp":1777936247724,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2011,11,29]],"date-time":"2011-11-29T00:00:00Z","timestamp":1322524800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Med"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:p>Among 320 patients with lower extremity peripheral artery disease (PAD) and low-density lipoprotein-cholesterol (LDL-C) levels &gt; 70 mg\/dl, we determined whether male sex, higher education, and greater self-efficacy for willingness to request therapy from one\u2019s physician were associated with increases in LDL-C-lowering medication and achievement of an LDL-C level &lt; 70 mg\/dl at 1-year follow-up. Participants were enrolled in a randomized controlled clinical trial to determine whether a telephone counseling intervention can help PAD patients achieve an LDL-C level &lt; 70 mg\/dl, compared to usual care and attention control conditions, respectively. Adjusting for age, race, comorbidities, PAD severity, and other covariates, male sex (odds ratio = 3.33, 95% confidence interval = 1.64 to 6.77, p = 0.001) was associated with a higher likelihood of adding cholesterol-lowering medication during follow-up, but was not associated with achieving an LDL-C &lt; 70 mg\/dl (odds ratio = 1.09, 95% confidence interval = 0.55 to 2.18). No associations of education level or self-efficacy with study outcomes were identified. In conclusion, male PAD patients with baseline LDL-C levels \u2265 70 mg\/dl were more likely to intensify LDL-C-lowering medication during 1-year follow-up than female PAD patients. Despite greater increases in LDL-C-lowering medication among female PAD patients, there was no difference in the degree of LDL-C lowering during the study between men and women with PAD. Clinical Trial Registration \u2013 URL: http:\/\/www.clinicaltrials.gov\/ct2\/show\/NCT00217919<\/jats:p>","DOI":"10.1177\/1358863x11425879","type":"journal-article","created":{"date-parts":[[2011,11,30]],"date-time":"2011-11-30T09:17:59Z","timestamp":1322644679000},"page":"428-435","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Gender differences in cholesterol-lowering medication prescribing in peripheral artery disease"],"prefix":"10.1177","volume":"16","author":[{"given":"Mary M","family":"McDermott","sequence":"first","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Greenland","sequence":"additional","affiliation":[{"name":"Northwestern University Feinberg School of Medicine, Chicago, IL, 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