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Early studies suggest that imaging-guided, catheter-based endovascular therapy can eliminate iliac vein obstruction and saphenous venous valvular reflux, resulting in reduced PTS severity; however, these observations have not been rigorously validated. A multidisciplinary expert panel meeting was convened to plan a multicenter randomized controlled clinical trial to evaluate endovascular therapy for the treatment of advanced PTS. This article summarizes the findings of the panel, and is expected to assist in developing a National Institutes of Health-sponsored clinical trial and other studies to improve the care of patients with advanced PTS.<\/jats:p>","DOI":"10.1177\/1358863x16650747","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T21:08:11Z","timestamp":1464728891000},"page":"400-407","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":45,"title":["Endovascular therapy for advanced post-thrombotic syndrome: Proceedings from a multidisciplinary consensus panel"],"prefix":"10.1177","volume":"21","author":[{"given":"Suresh","family":"Vedantham","sequence":"first","affiliation":[{"name":"Washington University in St Louis, St Louis, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan R","family":"Kahn","sequence":"additional","affiliation":[{"name":"SMBD Jewish General Hospital, 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