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Relevant articles were identified from electronic databases using key search terms: \u2018peripheral artery disease\u2019; \u2018limb ischaemia\u2019; \u2018intermittent claudication\u2019; \u2018knowledge\u2019; \u2018understanding\u2019; \u2018public\u2019; \u2018medical professional\u2019. The heterogeneous results were described narratively. A lack of knowledge and understanding of PAD (disease awareness) were identified in all groups. Among nsHCPs, factors which affect knowledge include the level of training, early clinical exposure and the presence of family members with cardiovascular\/vascular disease. Within the general public, knowledge and awareness was improved if a family member\/friend had a diagnosis, or following a patient-centred consultation with any HCP. Public campaigns are proven effective in improving disease knowledge\/awareness in conditions such as stroke alongside sustained patient education. These may provide future avenues to improve PAD knowledge and awareness, in order to effectively manage risk factors and minimise delayed or missed diagnosis of PAD. 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