{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:27:36Z","timestamp":1780500456102,"version":"3.54.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,5,21]],"date-time":"2023-05-21T00:00:00Z","timestamp":1684627200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"VA Clinical Science Research and Development","award":["1\/01CX001549"],"award-info":[{"award-number":["1\/01CX001549"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Med"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We aimed to describe patient and limb outcomes in the decade after endovascular revascularization for chronic lower-extremity peripheral artery disease (PAD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We assessed outcomes in patients having endovascular revascularization of the superficial femoral artery in two centers between 2003 and 2011 and followed for a median 9.3 (25\u201375%: 6.8, 11.1) years. Outcomes included death, myocardial infarction, stroke, repeat limb revascularizations, and amputations. We used competing risks analysis with clustering by patient to determine the hazard ratios (HR) and 95% CI for patients, and procedural characteristics for cause of death, cardiovascular events, and major adverse limb events (MALE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There were 253 index limb revascularizations in 202 patients followed for a median 9.3 years. Patients had intensive medical treatment with 90% on statins and 80% on beta-blockers. During follow up there were 57 (28%) cardiovascular deaths and 62 (31%) noncardiovascular deaths. Of the 253 limbs, 227 (90%) were free of MALE over follow up and 93 (37%) had MALE or minor repeat revascularization. In multivariable models, cardiovascular death significantly associated with critical limb ischemia (HR = 3.21, 95% CI = 1.84, 5.61) and noncardiovascular death with chronic kidney disease (HR = 2.69, 95% CI = 1.68, 4.30), and smoking (HR = 2.75, 95% CI = 1.01, 7.52). MALE or minor repeat revascularization associated with critical limb ischemia (HR = 1.43, 95% CI = 0.84, 2.43), smoking (HR = 2.49, 95% CI = 1.26, 4.90), and lesion length &gt; 200 mm (HR = 1.51, 95% CI = 0.98, 2.33).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Among patients with intensive medical therapy, the risk of noncardiovascular death was high and similar to cardiovascular death. Endovascular intervention can have acceptable long-term results. Future studies should evaluate strategies to reduce both cardiovascular and noncardiovascular deaths.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1358863x231174052","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T01:49:02Z","timestamp":1684720142000},"page":"290-298","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Patient and limb outcomes 10 years after endovascular revascularization of the superficial femoral artery for peripheral artery disease: The Boston Femoral Artery Endovascular Revascularization Outcomes (Boston FAROUT) study"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-9136","authenticated-orcid":false,"given":"Scott","family":"Kinlay","sequence":"first","affiliation":[{"name":"Cardiovascular Division, Department of Medicine, Veterans Affairs Boston Healthcare System, West Roxbury, MA, USA"},{"name":"Cardiovascular Division, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA, USA"},{"name":"Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Sobieszczyk","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA, USA"},{"name":"Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C","family":"Eisenhauer","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA, USA"},{"name":"Central Maine Medical Center, Lewiston, ME, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Ostrowski","sequence":"additional","affiliation":[{"name":"University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas M","family":"Todoran","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina, Charleston, SC, USA"},{"name":"Cardiovascular Division, Department of Medicine, Ralph H Johnson Veterans Affairs Medical Center, Charleston, SC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,21]]},"reference":[{"key":"bibr1-1358863X231174052","volume":"135","author":"Gerhard-Herman MD","year":"2017","journal-title":"Circulation"},{"key":"bibr2-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx095"},{"key":"bibr3-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2019.10.025"},{"key":"bibr4-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.046"},{"key":"bibr5-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.07.034"},{"key":"bibr6-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.06.041"},{"key":"bibr7-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.003219"},{"key":"bibr8-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.017719"},{"key":"bibr9-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.032235"},{"key":"bibr10-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32409-1"},{"key":"bibr11-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2021372"},{"key":"bibr12-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1707914"},{"key":"bibr13-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1912388"},{"key":"bibr14-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.04.083"},{"key":"bibr15-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.02.018"},{"key":"bibr16-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.016900"},{"key":"bibr17-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007702"},{"key":"bibr18-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.07.023"},{"key":"bibr19-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.12.034"},{"key":"bibr20-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2021.2738"},{"key":"bibr21-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.04.391"},{"key":"bibr22-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.11.083"},{"key":"bibr23-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.019355"},{"key":"bibr24-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.08.064"},{"key":"bibr25-1358863X231174052","unstructured":"US Department of Veterans Affairs. National Center for Veterans Analysis and Statistics. Table 8L: Vetpop2018 Living by State, Race\/Ethnicity, Gender 2018\u20132048, https:\/\/www.va.gov\/vetdata\/stateSummaries.asp (2017, accessed 21 March 2022)."},{"key":"bibr26-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7954-4-7"},{"key":"bibr27-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.2009.08.0122"},{"key":"bibr28-1358863X231174052","unstructured":"VA Office of Health Equity. National Veteran Health Equity Report\u2014FY2013. US Department of Veterans Affairs, Washington, DC, http:\/\/www.va.gov\/healthequity\/NVHER.asp (2016, accessed 21 March 2022)."},{"key":"bibr29-1358863X231174052","unstructured":"Opportunities Exist for VA to Better Identify and Address Racial and Ethnic Disparities. US Government Accountability Office, GAO-20-83, https:\/\/www.gao.gov\/assets\/710\/706431.pdf (2019, 5 March 2022)."},{"key":"bibr30-1358863X231174052","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.01.013"},{"key":"bibr31-1358863X231174052","unstructured":"United States Food and Drug Administration. Paclitaxel-coated balloons and stents for peripheral artery disease. https:\/\/www.fda.gov\/medical-devices\/cardiovascular-devices\/paclitaxel-coated-balloons-and-stents-peripheral-arterial-disease (2021, accessed 5 March 2023)."}],"container-title":["Vascular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1358863X231174052","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1358863X231174052","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1358863X231174052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:33:56Z","timestamp":1777692836000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1358863X231174052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,21]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1177\/1358863X231174052"],"URL":"https:\/\/doi.org\/10.1177\/1358863x231174052","relation":{},"ISSN":["1358-863X","1477-0377"],"issn-type":[{"value":"1358-863X","type":"print"},{"value":"1477-0377","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,21]]}}}