{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:15:47Z","timestamp":1777936547587,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vasc Med"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The long-term effects of supervised exercise training (SET) on functional performance and health-related quality of life (HRQoL) in symptomatic peripheral artery disease (PAD) are poorly investigated, especially in women. This study investigated these outcomes 1 year after SET in both women and men.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this single-arm, prospective, nonrandomized study, patients with symptomatic PAD participating in the 3-month SET program were investigated. Functional performance (6-minute walking distance [6MWD], the stair-climbing test [SCT], and the short physical performance battery [SPPB]), and HRQoL (physical component summary [PCS] score of the Short Form-36 questionnaire) were assessed before and following SET, as well as at 6 and 12 months after SET completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Ninety patients (women:\n                      <jats:italic>n<\/jats:italic>\n                      = 30; men:\n                      <jats:italic>n<\/jats:italic>\n                      = 60) with chronic symptomatic PAD (ankle\u2013brachial index 0.78 \u00b1 0.22; mean age 65.4 \u00b1 10.2 years) were included in the study. The 6MWD (\n                      <jats:italic>women<\/jats:italic>\n                      : before: 387.2 \u00b1 88.6 m; after: 472.4 \u00b1 57.0 m; 12 months: 469.9 \u00b1 57.8 m;\n                      <jats:italic>men<\/jats:italic>\n                      : before: 431.7 \u00b1 94.0 m; after: 477.5 \u00b1 88.6 m; 12 months: 467.2 \u00b1 73.4 m), SPPB score (\n                      <jats:italic>women<\/jats:italic>\n                      : before: 9.6 \u00b1 2.4; after: 11.3 \u00b1 1.0; 12 months: 11.2 \u00b1 0.5;\n                      <jats:italic>men<\/jats:italic>\n                      : before: 10.6 \u00b1 1.4; after: 11.5 \u00b1 0.9; 12 months: 11.3 \u00b1 0.8), and SCT (\n                      <jats:italic>women<\/jats:italic>\n                      : before: 8.6 \u00b1 4.4 s; after: 5.6 \u00b1 1.6 s; 12 months: 5.8 \u00b1 1.2 s;\n                      <jats:italic>men<\/jats:italic>\n                      : before: 6.2 \u00b1 2.3 s; after: 5.0 \u00b1 1.9 s; 12 months: 5.3 \u00b1 1.6 s) significantly improved over time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2264 0.001), with no significant differences between women and men. The PCS score (\n                      <jats:italic>women<\/jats:italic>\n                      : before: 30.3 \u00b1 8.0; after: 38.8 \u00b1 8.4; 12 months: 35.7 \u00b1 7.4;\n                      <jats:italic>men<\/jats:italic>\n                      : before: 32.4 \u00b1 10.5; after: 35.7 \u00b1 9.5; 12 months: 35.4 \u00b1 7.6) significantly improved in women only (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.020).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>One year after SET, both women and men with PAD exhibit similar functional benefits, whereas HRQoL improvements were observed exclusively in women.<\/jats:p>\n                  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