{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T18:19:27Z","timestamp":1784744367444,"version":"3.55.0"},"reference-count":42,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Child Psychol Psychiatry"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>We aimed to investigate the characteristics of adolescents with Bipolar disorder-I with irritability and agitation (Mania+IA) compared to those without irritability and agitation (Mania-IA) in a multi-center representative sample.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data of 145 patients from three tertiary-care inpatient units between 2016 and 2021 were obtained. Psychomotor agitation was defined as a score of \u22653 on the YMRS \u201cIncreased Motor Activity\u2013\u2013Energy\u201d item, irritability as a score of \u22654 on the YMRS \u2018irritability\u2019 item, and severity anchors of speech and thought disturbance on the YMRS \u20186 and 7\u2019 items.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Previous manic episodes ( p = 0.013), involuntary hospitalization ( p = 0.006), psychotic features ( p = 0.001), formal thought disorder ( p = 0.010) and aggressive\/disruptive behavior ( p = 0.021) were more frequent in the Mania+IA group. Conversely, depressive episodes ( p = 0.006) and family history of depression ( p = 0.024) were more frequent in the Mania-IA group. The Mania+IA had poorer functioning at the time of discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Irritability and agitation were closely related to complications, psychotic symptoms and thought disorder. Assessment and monitoring of psychomotor agitation and irritability may help child and adolescent psychiatrists to predict clinical difficulties and appropriate interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13591045221125331","type":"journal-article","created":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T06:00:57Z","timestamp":1662098457000},"page":"1266-1278","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Psychomotor agitation and irritability in adolescents with manic episode: Clinical data from three inpatient units"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6548-0629","authenticated-orcid":false,"given":"Serkan","family":"Turan","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Uludag University School of Medicine, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8412-8049","authenticated-orcid":false,"given":"\u00c7a\u011fatay","family":"Ermi\u015f","sequence":"additional","affiliation":[{"name":"Diyarbak\u0131r State Hospital, Diyarbak\u0131r, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u015eafak","family":"Eray","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Uludag University School of Medicine, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilay","family":"A\u011fa\u00e7","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Dokuz Eylul University School of Medicine, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sena","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Bal\u0131kesir Atat\u00fcrk City Hospital, Bal\u0131kesir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Sena","family":"Y\u00fcksel","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Bakirkoy Prof Dr Mazhar Osman Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u00e7a","family":"Bezir Karaca","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Uludag University School of Medicine, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duru","family":"G\u00fcler","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Dokuz Eylul University School of Medicine, \u0130zmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Tun\u00e7t\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Bakirkoy Prof Dr Mazhar Osman Research and Training Hospital for Psychiatry, Neurology and Neurosurgery, University of Health Sciences, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remzi O\u011fulcan","family":"\u00c7\u0131ray","sequence":"additional","affiliation":[{"name":"Mardin State Hospital, Mardin, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caner","family":"Mutlu","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Uludag University School of Medicine, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fcl","family":"Kara\u00e7etin","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Bakirkoy 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