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Four men and four women with pre-existing mental health problems who had received hepatitis C virus treatment took part in semi-structured interviews which were analysed using interpretative phenomenological analysis. A central theme of \u2018Self, stigma and change\u2019 was identified which interlinked with three other main themes of \u2018Coping and responding to treatment\u2019, \u2018Connectedness to others\u2019 and \u2018The impact of information\u2019. 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