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This systematic review was conducted to examine the psychological and health-related quality-of-life outcomes of Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser syndrome. In total, 22 articles identified through electronic search matched the inclusion criteria and were included in our review. Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser syndrome may be associated with psychological symptoms and impaired quality of life, but especially with poor sexual esteem and genital image. Women may experience difficulties managing intimacy and disclosing to partners. Mothers may be perceived as overinvolved, with consequent negative emotions in women with the disease.<\/jats:p>","DOI":"10.1177\/1359105319901308","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T06:33:29Z","timestamp":1579588409000},"page":"26-39","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Psychological impact and health-related quality-of-life outcomes of Mayer\u2013Rokitansky\u2013K\u00fcster\u2013Hauser syndrome: A systematic review and narrative synthesis"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8944-1440","authenticated-orcid":false,"given":"Federica","family":"Facchin","sequence":"first","affiliation":[{"name":"Catholic University of the Sacred Heart, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Francini","sequence":"additional","affiliation":[{"name":"Catholic 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