{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T19:04:34Z","timestamp":1785179074249,"version":"3.55.0"},"reference-count":60,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"This work was supported by Current Research Funds 2024, Ministry of Health, Italy."}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Health Psychol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>\n                    Parkinson\u2019s Disease (PD) is a progressive neurodegenerative disorder affecting motor and cognitive functions, reducing the quality of life (QoL) for both patients and caregivers. This study explored correlations between clinical and psychological factors in early-stage PD patients and their caregivers, focusing on disease burden and caregiver stress. Nineteen PD patients and their caregivers were assessed. For patients, we evaluated disease severity (Hoehn and Yahr), cognitive functions (Montreal Cognitive Assessment, MoCA), anxiety levels (Hamilton Rating Scale for Anxiety, HRS-A), and quality of life (Parkinson\u2019s Disease Questionnaire, PDQ-39). For caregiver, we assessed caregiver burden (Caregiver Burden Inventory, CBI), functional social support (Family Strain Questionnaire, FSQ), and anxiety level (HRS-A). Spearman\u2019s correlation analyzed relationships between patient factors and caregiver burden. Cognitive impairment (MoCA) negatively correlated with patient QoL (PDQ-Cogn;\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.48,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.04). Caregiver anxiety (HRS-A) was positively correlated with physical (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.65,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003) and emotional stress (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.57,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.01), and higher family stress (FSQ). Our study highlights the complex relationships between clinical and psychological factors in PD patients and their caregivers. This supports the need for integrated approaches that address the clinical management of PD and the caregivers\u2019 psychological well-being.\n                  <\/jats:p>","DOI":"10.1177\/13591053241312505","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T02:00:51Z","timestamp":1737684051000},"page":"3169-3181","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Comprehensive assessment of caregiver burden and strain in early-stage Parkinson\u2019s disease: An exploratory study"],"prefix":"10.1177","volume":"30","author":[{"given":"Maria Grazia","family":"Maggio","sequence":"first","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9619-3983","authenticated-orcid":false,"given":"Laura","family":"Culicetto","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilla","family":"Bonanno","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosaria","family":"De Luca","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Corallo","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Rizzo","sequence":"additional","affiliation":[{"name":"University of Messina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Marino","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Quartarone","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonina","family":"Luca","sequence":"additional","affiliation":[{"name":"Kore University of Enna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Nicoletti","sequence":"additional","affiliation":[{"name":"University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocco Salvatore","family":"Calabr\u00f2","sequence":"additional","affiliation":[{"name":"IRCCS Centro Neurolesi Bonino Pulejo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/08919887231195219"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1166(199910)14:10<866::AID-GPS38>3.0.CO;2-Z"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.174.6.505"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870130108"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-240056"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2012.11.001"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25664"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0072-9752(07)83018-1"},{"issue":"5","key":"e_1_3_2_10_1","first-page":"1303","article-title":"Perceived stress, resilience, and health-related quality of life among Parkinson\u2019s disease caregivers in Mexico","volume":"27","author":"Ertl MM","year":"2019","unstructured":"Ertl MM, Trapp SK, Gonz\u00e1lez Arredondo S, et al. 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