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However, limited research has explored the experiences of those not able to benefit from ETI due to genetic factors. Seven adults with CF participated in semi-structured interviews, and data were analysed using Interpretative Phenomenological Analysis (IPA). Four themes emerged: \u2018feeling forgotten\u2019, (the challenges of being in a minority group); \u2018conflicted emotions\u2019, (the emotional impact of comparing one\u2019s situation with others); \u2018fragility of hope\u2019, (the journey of hope experienced by participants); and \u2018remaining on the old CF trajectory\u2019, (the ongoing challenges of living with CF). The findings suggest a need for improved communication, psychological and peer support, inclusive media representation and opportunities for active involvement in research and advocacy. 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