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This study investigated 1586 male SUD patients (mean age\u2009=\u200935.91) in a Chinese drug rehabilitation center, using network analysis and Directed Acyclic Graphs (DAGs) to analyze their anxiety and depression. Results showed that\n                    <jats:italic toggle=\"yes\">fear<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">dizziness<\/jats:italic>\n                    were the most central symptoms in the anxiety network and\n                    <jats:italic toggle=\"yes\">confusion<\/jats:italic>\n                    was the most central symptom in the depression network. In the comorbidity network,\n                    <jats:italic toggle=\"yes\">apprehension<\/jats:italic>\n                    was the key bridge symptom, and DAG further indicated\n                    <jats:italic toggle=\"yes\">mental disintegration<\/jats:italic>\n                    as a triggering symptom for both anxiety and depression. These findings may indicate\n                    <jats:italic toggle=\"yes\">fear<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">dizziness, confusion<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">apprehension<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">mental disintegration<\/jats:italic>\n                    as relatively important symptoms, providing potential directions for future intervention research aimed at reducing comorbidity of anxiety and depression in SUD patients.\n                  <\/jats:p>","DOI":"10.1177\/13591053261488514","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:57:47Z","timestamp":1790859467000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Anxiety and depression symptoms in Chinese male patients with substance use disorder: Independent and comorbid networks"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8830-2807","authenticated-orcid":false,"given":"Siying","family":"Li","sequence":"first","affiliation":[{"name":"Faculty of Psychology, Southwest University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6241-882X","authenticated-orcid":false,"given":"Yunhan","family":"He","sequence":"additional","affiliation":[{"name":"School of Psychology, Shenzhen University, Shenzhen, China"},{"name":"The Shenzhen Humanities &amp; Social Sciences Key Research Bases of the Center for Mental Health, Shenzhen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8414-7955","authenticated-orcid":false,"given":"Chunjing","family":"He","sequence":"additional","affiliation":[{"name":"Faculty of Psychology, Southwest University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1437-9539","authenticated-orcid":false,"given":"Hong Mian","family":"Yang","sequence":"additional","affiliation":[{"name":"Faculty of Health and Wellness, City University of Macau, Macao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3929-4075","authenticated-orcid":false,"given":"Yuxi","family":"Nie","sequence":"additional","affiliation":[{"name":"Faculty of Psychology, Southwest University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4315-659X","authenticated-orcid":false,"given":"Yonglong","family":"Tang","sequence":"additional","affiliation":[{"name":"Faculty of Psychology, Southwest University, Chongqing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"crossref","unstructured":"Agosti V (2013) Predictors of alcohol dependence relapse during recurrence of major depression. 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