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Data of a gastric ulcer patient who suffered from hiccups, with brainstem encephalitis detected and then subsequently suffered from duodenal perforation were collected retrospectively and analyzed. A literature search was conducted on Epstein\u2013Barr virus associated encephalitis using keywords like \u201cEpstein\u2013Barr virus encephalitis\u201d and \u201cbrainstem encephalitis,\u201d \u201chiccup.\u201d The etiology of EBV-related brainstem encephalitis in this case report is not clear. However, from the initial hiccup to the presentation of both brainstem encephalitis and duodenal perforation during the course of hospitalizations builds up an uncommon case.<\/jats:p>","DOI":"10.1177\/13596535231161488","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T05:38:47Z","timestamp":1677735527000},"page":"135965352311614","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case report and literature review: A hiccup patient developed encephalitis and duodenal perforation"],"prefix":"10.1177","volume":"28","author":[{"given":"Fanfeng","family":"Kong","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Changzhou Second People\u2019s Hospital Affiliated to Nanjing Medical University, Changzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9639-4010","authenticated-orcid":false,"given":"Xiao 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