{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T09:00:12Z","timestamp":1777453212151,"version":"3.51.4"},"reference-count":44,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministarstvo nauke, tehnolo\u0161kog razvoja i inovacija Republike Srbije","doi-asserted-by":"publisher","award":["Contract No#451-03-47\/2023-01\/200017"],"award-info":[{"award-number":["Contract No#451-03-47\/2023-01\/200017"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Antiviral Therapy"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>Background: Subacute thyroiditis (SAT) is an organ-specific disease that various drugs, including COVID-19 vaccines, can trigger. COVID-19 infection has been associated with thyroid gland damage and disease SARS-CoV-2 direct action, euthyroid sick syndrome, and immune-mediated mechanisms are all potential mechanisms of thyroid damage. It denotes thyroid gland inflammation, most commonly of viral origin, and belongs to the transitory, self-limiting thyroid gland diseases group, causing complications in approximately 15% of patients in the form of permanent hypothyroidism. Some authors say SAT is the most common thyroid disease associated with COVID-19.<\/jats:p>\n                  <jats:p>Purpose: The occurrence of SAT many weeks after administering the second COVID-19 vaccine is rare and has limited documentation in academic literature. This study aims to present the occurrence of SAT after administering the COVID-19 vaccine. We present the case of a 37-year-old man who developed SAT 23 days after receiving the second dose of Pfizer BioNTech's COVID-19 mRNA vaccine.<\/jats:p>\n                  <jats:p>Research design and study sample: Due to neck pain and an elevated body temperature (up to 38.2\u00b0C), a 37-year-old male subject presented for examination 23 days after receiving the second Pfizer BioNTech mRNA vaccine against SARS-CoV-2 viral infection. The patient denied ever having an autoimmune disease or any other disease. Painful neck palpation and a firm, slightly enlarged thyroid gland with no surrounding lymphadenopathy were identified during the exam. The heart rate was 104 beats per minute. All of the remaining physical findings were normal.<\/jats:p>\n                  <jats:p>Data collection and\/or Analysis: Data collected during the disease are integral to the medical record.<\/jats:p>\n                  <jats:p>Results: Hematology and biochemistry analyses at the initial and follow-up visits revealed minor leukocytosis, normocytic anaemia, and thrombocytosis, followed by a mild increase in lactate dehydrogenase and decreased iron levels. The patient's thyroid function and morphology had recovered entirely from post-vaccine SAT.<\/jats:p>\n                  <jats:p>Conclusions: Results from this study emphasise the need for healthcare professionals to promptly report any case of SAT related to COVID-19 vaccination. Further investigation is warranted to understand the immunopathogenesis of COVID-19-associated thyroiditis and the impact of COVID-19 immunization on this condition.<\/jats:p>","DOI":"10.1177\/13596535231208831","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T10:53:55Z","timestamp":1697799235000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Subacute thyroiditis following COVID-19 vaccination: Case presentation"],"prefix":"10.1177","volume":"28","author":[{"given":"Aleksandra Z","family":"Tomic","sequence":"first","affiliation":[{"name":"Clinic for Internal Medicine, Department of Endocrinology and Diabetes, Zemun Clinical Hospital, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5486-0079","authenticated-orcid":false,"given":"Sonja S","family":"Zafirovic","sequence":"additional","affiliation":[{"name":"Department of Radiobiology and Molecular Genetics, VIN\u010cA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoran M","family":"Gluvic","sequence":"additional","affiliation":[{"name":"Clinic for Internal Medicine, Department of Endocrinology and Diabetes, Zemun Clinical Hospital, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir S","family":"Samardzic","sequence":"additional","affiliation":[{"name":"Clinic for Internal Medicine, Department of Endocrinology and Diabetes, Zemun Clinical Hospital, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjana T","family":"Macvanin","sequence":"additional","affiliation":[{"name":"Department of Radiobiology and Molecular Genetics, VIN\u010cA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja LJ","family":"Radunovic","sequence":"additional","affiliation":[{"name":"Faculty of Stomatology, Pancevo, University Business Academy, Novi Sad, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esma R","family":"Isenovic","sequence":"additional","affiliation":[{"name":"Department of Radiobiology and Molecular Genetics, VIN\u010cA Institute of Nuclear Sciences - National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,20]]},"reference":[{"key":"bibr1-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-021-00408-x"},{"key":"bibr2-13596535231208831","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9040967"},{"key":"bibr3-13596535231208831","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2020.582932"},{"key":"bibr4-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1080\/15321819.2021.1951291"},{"key":"bibr5-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2020.06.003"},{"key":"bibr6-13596535231208831","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01880"},{"key":"bibr7-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2021.102792"},{"key":"bibr8-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-021-09648-y"},{"key":"bibr9-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-021-02734-w"},{"key":"bibr10-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab373"},{"key":"bibr11-13596535231208831","doi-asserted-by":"publisher","DOI":"10.1210\/jendso\/bvab048.1954"},{"key":"bibr12-13596535231208831","unstructured":"Helen T, John W. 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