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A sample of                 participants received a full diagnostic assessment, conducted blind to screen                 status. The sensitivity of the CAST, at a designated cut-point of 15, was 100                 percent, the specificity was 97 percent and the positive predictive value was 50                 percent, using the group\u2019s consensus diagnosis as the gold standard. The                 accuracy indices varied with the case definition used. The sensitivity of the                 accuracy statistics to case definition and to missing data was explored. The CAST is                 useful as a screening test for autism spectrum conditions in epidemiological                 research. 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