{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:07:45Z","timestamp":1791202065309,"version":"4.2.0"},"reference-count":45,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,5,15]],"date-time":"2012-05-15T00:00:00Z","timestamp":1337040000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Autism"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:p>We evaluated the proportion of individuals with Down syndrome (DS: N = 108) who met criteria for autism spectrum disorder (ASD) on the Social Communication Questionnaire and the severity of ASD-related symptomatology in this group. The proportions of individuals with DS meeting the cut-off for ASD and autism in this sample were 19% and 8%, respectively. We then evaluated the behavioural profile of individuals with DS who scored above cut-off for ASD (DS+ASD; N = 17) compared with those with DS-only (N = 17) and individuals with idiopathic ASD (N = 17), matched for adaptive behaviour skills and ASD symptom severity (ASD group only). Individuals in the DS+ASD and ASD-only groups showed more stereotyped behaviour, repetitive language, overactivity and self-injury than the DS-only group (p &lt; .001). Individuals in the DS+ASD and DS-only groups appeared less withdrawn from their surroundings than those with ASD (p &lt; .004). These findings indicate differences in the behavioural and cognitive profile of individuals with DS+ASD compared with those with DS-only, when controlling for adaptive behaviour skills. Individuals with DS+ASD show broad similarities with individuals with idiopathic ASD with regard to ASD and behavioural characteristics but may also show some areas of subtle difference from this group.<\/jats:p>","DOI":"10.1177\/1362361312442790","type":"journal-article","created":{"date-parts":[[2012,5,16]],"date-time":"2012-05-16T00:23:44Z","timestamp":1337127824000},"page":"390-404","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":93,"title":["Prevalence of autism spectrum disorder symptomatology and related behavioural characteristics in individuals with Down syndrome"],"prefix":"10.1177","volume":"17","author":[{"given":"Jo","family":"Moss","sequence":"first","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Birmingham, UK and Institute of Psychiatry, King\u2019s College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Richards","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Nelson","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Oliver","sequence":"additional","affiliation":[{"name":"Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Birmingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,5,15]]},"reference":[{"key":"bibr1-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2350-11-135"},{"key":"bibr2-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2010.01337.x"},{"key":"bibr3-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2003.00463.x"},{"key":"bibr4-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.175.5.444"},{"key":"bibr5-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00114"},{"key":"bibr6-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1097\/00004583-198807000-00011"},{"key":"bibr7-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2010.01338.x"},{"key":"bibr8-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30622"},{"key":"bibr9-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.b.30407"},{"key":"bibr10-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1097\/DBP.0b013e3181d5aa6d"},{"key":"bibr11-1362361312442790","volume-title":"Genetics and Mental Retardation Syndromes","author":"Dykens E. M.","year":"2000"},{"key":"bibr12-1362361312442790","first-page":"886","volume":"54","author":"Fisch G.","year":"2010","journal-title":"Journal of Intellectual Disability Research"},{"key":"bibr13-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291799008508"},{"key":"bibr14-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.1992.tb00563.x"},{"key":"bibr15-1362361312442790","volume-title":"The Biology of the Autistic Syndromes","author":"Gillberg C.","year":"2000","edition":"3"},{"key":"bibr16-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.149.1.68"},{"key":"bibr17-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2010.07.001"},{"key":"bibr18-1362361312442790","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1468-3148.2007.00368.x","volume":"21","author":"Hepburn S.","year":"2008","journal-title":"Journal of Applied Research in Intellectual Disabilities"},{"key":"bibr19-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1177\/1362361304042721"},{"key":"bibr20-1362361312442790","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1469-8749.1995.tb12024.x","volume":"37","author":"Howlin P.","year":"1995","journal-title":"Developmental Medicine and Child Neurology"},{"key":"bibr21-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1352\/0895-8017(2002)107<0146:SIBSRA>2.0.CO;2"},{"key":"bibr22-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1017\/S001216229900033X"},{"key":"bibr23-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1177\/1362361398023004"},{"key":"bibr24-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700054271"},{"key":"bibr25-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-007-0374-4"},{"key":"bibr26-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1988.tb06350.x"},{"key":"bibr27-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2008.01138.x"},{"key":"bibr28-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2788.2009.01197.x"},{"key":"bibr29-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordhb\/9780195305012.013.0018"},{"key":"bibr30-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-008-0655-6"},{"key":"bibr31-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1352\/0895-8017(2008)113[278:POASPI]2.0.CO;2"},{"key":"bibr32-1362361312442790","first-page":"1","volume":"1","author":"Mount R. H.","year":"2003","journal-title":"American Journal on Mental Retardation"},{"key":"bibr33-1362361312442790","author":"Oliver C.","journal-title":"Journal of Autism and Developmental Disorders"},{"key":"bibr34-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1179\/bjms.1982.011"},{"key":"bibr35-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33573"},{"key":"bibr36-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1017\/S0012162201001372"},{"key":"bibr37-1362361312442790","author":"Richards C.","journal-title":"Journal of Intellectual Disability Research"},{"key":"bibr38-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1016\/j.rasd.2009.01.012"},{"key":"bibr39-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1348\/014466503762842039"},{"key":"bibr40-1362361312442790","volume-title":"The Social Communication Questionnaire","author":"Rutter M.","year":"2003"},{"key":"bibr41-1362361312442790","volume-title":"Vineland Adaptive Behavior Scales, Second Edition","author":"Sparrow S.S.","year":"2005"},{"key":"bibr42-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-005-0010-0"},{"key":"bibr43-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1177\/1362361304042720"},{"key":"bibr44-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1177\/1362361397012005"},{"key":"bibr45-1362361312442790","doi-asserted-by":"publisher","DOI":"10.1007\/BF01531289"}],"container-title":["Autism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1362361312442790","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1362361312442790","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1362361312442790","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:50:24Z","timestamp":1777380624000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1362361312442790"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,15]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1177\/1362361312442790"],"URL":"https:\/\/doi.org\/10.1177\/1362361312442790","relation":{},"ISSN":["1362-3613","1461-7005"],"issn-type":[{"value":"1362-3613","type":"print"},{"value":"1461-7005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,15]]}}}