{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T01:39:28Z","timestamp":1778031568405,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T00:00:00Z","timestamp":1554336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100012779","name":"r\u00e9seau qu\u00e9b\u00e9cois de recherche sur les m\u00e9dicaments","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Autism"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:p>A number of cross-sectional studies report extensive use of psychiatric services and high healthcare costs in autistic youths. However, little is known about how the use of these services evolves from the time of diagnosis, as children grow up. Our objectives were to investigate the use, costs, and predictors of psychiatric services following autism spectrum diagnosis. We built a cohort of 1227 newly diagnosed autism spectrum individuals identified in the Quebec (Canada) R\u00e9gie de l\u2019assurance maladie du Qu\u00e9bec administrative database (January 1998 to December 2010). Mean number and cost per individual of psychiatric healthcare use (hospitalizations, medical visits, psychoactive drug use) were calculated yearly for 5\u2009years following autism spectrum diagnosis. Mean number of psychiatric visits decreased over time by more than threefold (7.5 vs 2.1 visits) from year 1 to year 5, whereas psychoactive drug use increased from 16.0 to 25.2 claims. Psychiatric hospitalizations decreased during follow-up, but still represented the greatest costs per individual (CAD9820 for year 1; CAD4628 for year 5). Antipsychotics represented over 50% of drug costs. Mixed-effect model with repeated measures showed that previous psychoactive drug use was the strongest predictor of greater psychiatric healthcare cost during follow-up (odds ratio: 9.96; 95% confidence interval: 7.58\u201313.10). These trends contrast with guidelines advocating cautious prescribing of antipsychotics with periodical re-assessment of their benefit.<\/jats:p>","DOI":"10.1177\/1362361319840229","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T04:50:04Z","timestamp":1554353404000},"page":"2020-2030","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Use, costs, and predictors of psychiatric healthcare services following an autism spectrum diagnosis: Population-based cohort study"],"prefix":"10.1177","volume":"23","author":[{"given":"Caroline","family":"Croteau","sequence":"first","affiliation":[{"name":"University of Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Mottron","sequence":"additional","affiliation":[{"name":"University of Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Dorais","sequence":"additional","affiliation":[{"name":"StatSciences Inc., Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Eric","family":"Tarride","sequence":"additional","affiliation":[{"name":"McMaster University, Canada"},{"name":"The Research Institute of St. Joseph\u2019s Hamilton, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Perreault","sequence":"additional","affiliation":[{"name":"University of Montreal, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,4]]},"reference":[{"key":"bibr1-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2016.1154536"},{"key":"bibr2-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2005.15.116"},{"key":"bibr3-1362361319840229","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.13ac08691"},{"key":"bibr4-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr5-1362361319840229","volume-title":"AHFS drug information","author":"American Society of Health Systems Pharmacist","year":"2016"},{"key":"bibr6-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1177\/1362361312467709"},{"key":"bibr7-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-012-1637-2"},{"key":"bibr8-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0127"},{"key":"bibr9-1362361319840229","doi-asserted-by":"publisher","DOI":"10.22374\/1710-6222.24.3.2"},{"key":"bibr10-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-015-2634-z"},{"issue":"2","key":"bibr11-1362361319840229","first-page":"1","volume":"63","author":"Developmental Disabilities Monitoring Network Surveillance Year 2010","year":"2014","journal-title":"MMWR Surveillance Summary"},{"key":"bibr12-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-009-0750-3"},{"key":"bibr13-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1177\/1362361303007003003"},{"key":"bibr14-1362361319840229","doi-asserted-by":"publisher","DOI":"10.1177\/070674371205700502"},{"key":"bibr15-1362361319840229","unstructured":"Institut national d\u2019excellenceen sant\u00e9 eten services sociaux. (2013). Portrait de l\u2019usage des m\u00e9dicaments chez les enfants et les adolescents ayant re\u00e7u un diagnostic de troubles du spectre de l\u2019autisme couverts par le r\u00e9gime public d\u2019assurance m\u00e9dicaments. In Turgeon M., Tremblay E., D\u00e9ry N., Gua H. (Eds.), INESSS. 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(2015). Consumer Price Index, health and personal care, by province, CANSIM, table 326-0021and catalogue nos. 62-001X and 62-010-X. 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