{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T20:35:52Z","timestamp":1777494952848,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"DePaul University College of Science and Health Faculty Summer Research Grant","award":["2016"],"award-info":[{"award-number":["2016"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Child Health Care"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>Hypermobile Ehlers\u2013Danlos syndrome (hEDS) includes physical symptoms of chronic pain, fatigue, gastrointestinal dysfunction, and joint subluxations\/dislocations. This study aims to fill a research gap regarding the psychosocial well-being in pediatric hEDS by assessing relationships between functional disability, social support, and mental health. Increased functional disability is hypothesized to be associated with increased mental health challenges, specifically anxiety and depression, and general social support is hypothesized to moderate this relationship, such that higher perceived social support will mitigate the negative psychological impacts of functional disability. Gender\u2019s influence on mental health in pediatric hEDS is also explored. Thirty-four youth with pediatric hEDS recruited from a United States Midwest multidisciplinary genetics clinic completed self-report questionnaires. Results demonstrate associations between functional disability and mental health, and social support and mental health independently; however, moderation was not found. Functional disability and social support each have a unique influence on the mental health of children with pediatric hEDS and should each receive clinical attention. Exploratory analyses into the influence of gender provide a groundwork for future studies.<\/jats:p>","DOI":"10.1177\/13674935221143822","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T03:58:01Z","timestamp":1670558281000},"page":"486-500","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["The role of functional disability and social support in psychological outcomes for individuals with pediatric hypermobile ehlers\u2013danlos syndrome"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7852-7353","authenticated-orcid":false,"given":"Keely H","family":"Bieniak","sequence":"first","affiliation":[{"name":"Department of Psychology, DePaul University College of Science and Health, Chicago, IL, USA"},{"name":"Department of Medical Genetics & Neurodevelopmental Center, Peyton Manning Children\u2019s Hospital, Indianapolis, IN, USA"},{"name":"Department of Psychology, DePaul University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad T","family":"Tinkle","sequence":"additional","affiliation":[{"name":"Department of Psychology, DePaul University College of Science and Health, Chicago, IL, USA"},{"name":"Department of Medical Genetics & Neurodevelopmental Center, Peyton Manning Children\u2019s Hospital, Indianapolis, IN, USA"},{"name":"Department of Psychology, DePaul University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5501-6825","authenticated-orcid":false,"given":"Susan T","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Psychology, DePaul University College of Science and Health, Chicago, IL, USA"},{"name":"Department of Medical Genetics & Neurodevelopmental Center, Peyton Manning Children\u2019s Hospital, Indianapolis, IN, USA"},{"name":"Department of Psychology, DePaul University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,12,9]]},"reference":[{"key":"bibr1-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1097\/JXX.0000000000000672"},{"key":"bibr2-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4003-7"},{"key":"bibr3-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980428)77:1<31::AID-AJMG8>3.0.CO;2-O"},{"key":"bibr4-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1037\/cpp0000411"},{"key":"bibr5-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31544"},{"key":"bibr6-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000406"},{"key":"bibr7-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33585"},{"key":"bibr8-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-016-0922-6"},{"key":"bibr9-13674935221143822","first-page":"624","volume":"29","author":"Chu PS","year":"2010","journal-title":"Journal of Submicroscopic Cytology and Pathology"},{"key":"bibr10-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.98.2.310"},{"key":"bibr11-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsu003"},{"key":"bibr12-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-199706000-00006"},{"key":"bibr13-13674935221143822","first-page":"42","volume":"3","author":"Friedrichsdorf SJ","year":"2016","journal-title":"Children (Basel, Switzerland)"},{"key":"bibr14-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1037\/a0014232"},{"key":"bibr15-13674935221143822","volume-title":"Social Support Scale for Children: Manual and Questionnaires","author":"Harter S","year":"2012"},{"key":"bibr16-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-015-3375-1"},{"key":"bibr18-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-010-9619-3"},{"key":"bibr19-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.02.050"},{"key":"bibr20-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/art.24099"},{"key":"bibr21-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.03.004"},{"key":"bibr22-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.07.016"},{"key":"bibr23-13674935221143822","author":"Levy HP","year":"2018","journal-title":"GeneReviews"},{"key":"bibr24-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2007.12.002"},{"key":"bibr25-13674935221143822","volume-title":"Significance of the difference between two correlation coefficients","author":"Lowry R","year":"2021"},{"key":"bibr26-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31552"},{"key":"bibr27-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.61055"},{"key":"bibr28-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.36293"},{"key":"bibr30-13674935221143822","volume-title":"Disentangling the Sleep-Pain Relationship in Pediatric Chronic Pain: The Mediating Role of Internalizing Mental Health Symptoms","author":"Pavlova M","year":"2017"},{"key":"bibr31-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7028.37.2.190"},{"key":"bibr32-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s10964-006-9070-5"},{"key":"bibr33-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1093\/med:psych\/9780195123630.003.0018"},{"key":"bibr34-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2007.05.001"},{"key":"bibr35-13674935221143822","first-page":"93","volume":"17","author":"Simons LE","year":"2012","journal-title":"Journal of pain research"},{"key":"bibr36-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.10.032"},{"key":"bibr37-13674935221143822","first-page":"S166","volume":"35","author":"Syx D","year":"2017","journal-title":"Clinical and Experimental Rheumatology"},{"key":"bibr38-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2015.06.009"},{"key":"bibr39-13674935221143822","volume-title":"American Journal of Medical Genetics Part C: Seminars in Medical Genetics","author":"Tinkle B","year":"2017"},{"key":"bibr40-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1177\/1367493519867174"},{"key":"bibr41-13674935221143822","volume-title":"Ehlers-Danlos syndrome","author":"U.S. National Library of Medicine","year":"2020"},{"key":"bibr42-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-013-0544-0"},{"key":"bibr43-13674935221143822","doi-asserted-by":"publisher","DOI":"10.3390\/children3040040"},{"key":"bibr44-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2009.12.026"},{"key":"bibr17-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1192\/S0007125000298474"},{"key":"bibr45-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/16.1.39"},{"key":"bibr46-13674935221143822","first-page":"279","volume-title":"Advances in pediatric psychology. Stress and coping in child health","author":"Wallander JL","year":"1992"},{"key":"bibr47-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/14.2.157"},{"key":"bibr48-13674935221143822","doi-asserted-by":"publisher","DOI":"10.1007\/s11205-014-0739-y"}],"container-title":["Journal of Child Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13674935221143822","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13674935221143822","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13674935221143822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:59:35Z","timestamp":1777388375000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13674935221143822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,9]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1177\/13674935221143822"],"URL":"https:\/\/doi.org\/10.1177\/13674935221143822","relation":{},"ISSN":["1367-4935","1741-2889"],"issn-type":[{"value":"1367-4935","type":"print"},{"value":"1741-2889","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,9]]}}}