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A study by Lin et al. has indicated that the cerebellum is part of the integrated network in amnestic mild cognitive impairment (aMCI), a prodromal state of Alzheimer's disease. The aMCI patients exhibited weaker cerebello-parietal functional connectivity but stronger cerebellar coupling with precuneus cortex, posterior cingulate gyrus, and caudate nucleus. These alterations in cerebello-cortical connectivity correlated with cognitive performance, suggesting a dynamic change of cerebello-cortical network related to cognitive change in aMCI.<\/jats:p>","DOI":"10.1177\/13872877241283678","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T01:50:42Z","timestamp":1732499442000},"page":"30-32","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["The emerging role of the cerebellum in neurodegeneration linked to cognitive impairment"],"prefix":"10.1177","volume":"102","author":[{"given":"Yicheng","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center and the New York Presbyterian Hospital, New York, NY, USA"},{"name":"Initiative for Columbia Ataxia and Tremor, Columbia University Irving Medical Center, New York, NY, USA"},{"name":"Taipei Municipal Gan-Dau Hospital, Taipei Veterans General Hospital Branch, Taipei, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9412-931X","authenticated-orcid":false,"given":"Sheng-Han","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center and the New York Presbyterian Hospital, New York, NY, USA"},{"name":"Initiative for Columbia Ataxia and Tremor, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,3]]},"reference":[{"key":"bibr1-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-070918-050258"},{"key":"bibr2-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2012.00031"},{"key":"bibr3-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00339.2011"},{"key":"bibr4-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.08.039"},{"key":"bibr5-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12853"},{"key":"bibr6-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00430"},{"key":"bibr7-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10486-w"},{"key":"bibr8-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2019.00072"},{"key":"bibr9-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-019-01099-1"},{"key":"bibr10-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-240368"},{"key":"bibr11-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.645171"},{"key":"bibr12-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1159\/000335876"},{"key":"bibr13-13872877241283678","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2014.00223"},{"key":"bibr14-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.02.018"},{"key":"bibr15-13872877241283678","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2019.01.004"}],"container-title":["Journal of Alzheimer\u2019s Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13872877241283678","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13872877241283678","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13872877241283678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:08:59Z","timestamp":1777370939000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13872877241283678"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,3]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1177\/13872877241283678"],"URL":"https:\/\/doi.org\/10.1177\/13872877241283678","relation":{},"ISSN":["1387-2877","1875-8908"],"issn-type":[{"value":"1387-2877","type":"print"},{"value":"1875-8908","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,3]]}}}