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Stratified Cox proportional hazard regression was used to calculate the adjusted hazard ratio (HR), with 95% confidence interval, for the risk of developing dementia in the two cohorts.\n                    <jats:bold>Results:<\/jats:bold>\n                    Patients with epilepsy but no history of TBI had increased risk of dementia (adjusted HR\u2009=\u20091.84). For patients aged 55\u201364 years, the adjusted HR for dementia was 4.5-fold higher among females in the study cohort than among males. Additionally, this study revealed that risk of dementia among above 75-year population lowest than other age subgroups (adjusted HR\u2009=\u20091.45).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    The study demonstrated an association between dementia and epilepsy in the patients who had no history of TBI. The effect was pronounced in patients aged 55\u201364 years, especially in the female population, suggesting that epilepsy needs to be more intensively prevented and controlled in this age group.\n                  <\/jats:p>","DOI":"10.1177\/13872877241312985","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T05:14:11Z","timestamp":1737609251000},"page":"1171-1179","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Dementia and epilepsy without traumatic brain injury among subjects middle-aged females: a population-based case-control study"],"prefix":"10.1177","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3685-8765","authenticated-orcid":false,"given":"Shu-Fen","family":"Chu","sequence":"first","affiliation":[{"name":"College of Nursing and Health Management, Shanghai University of Medicine and Health Sciences, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Hua","family":"Ni","sequence":"additional","affiliation":[{"name":"School of Nursing, College of Nursing, Taipei Medical University, Taipei"},{"name":"Research Center in Nursing Clinical Practice, Wan Fang Hospital, Taipei Medical University, Taipei"},{"name":"Department of Nursing, Wan Fang Hospital, Taipei Medical University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1047-9743","authenticated-orcid":false,"given":"Kuo-Hsing","family":"Liao","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei"},{"name":"Division of Critical Medicine, Department of Emergency and Critical Medicine, Wan Fang Hospital, Taipei Medical University, Taipei"},{"name":"Department of Neurotraumatology and Intensive Care, Taipei Neuroscience Institute, Taipei Medical University, Taipei"},{"name":"Division of Neurosurgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9152-7286","authenticated-orcid":false,"given":"Ya-Ting","family":"Wen","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Wan Fang Hospital, Taipei Medical University, Taipei"},{"name":"Division of Neurosurgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei"},{"name":"Taipei Neuroscience Institute, Taipei Medical University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,1,23]]},"reference":[{"key":"e_1_3_4_2_2","article-title":"Multi-domain prognostic models used in middle-aged adults without known cognitive impairment for predicting subsequent dementia","volume":"6","author":"Mohanannair Geethadevi G","year":"2023","unstructured":"Mohanannair Geethadevi G, Quinn TJ, George J, et al. 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