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However, their relationship with subjective cognitive decline plus (SCD-plus), a potential biomarker of preclinical Alzheimer's disease (AD), remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the association between NSI, HDS and SCD-plus among older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study utilized data from the Hubei Memory and Aging Cohort Study (HMACS, 2018\u20132022), examining the relationship between HDS, NSI, and SCD-plus status and feature scores, using logistic and linear regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 3514 adults (age:\u2009\u2265\u200965 y; female: 52.44%), 1329 had SCD-plus status (37.82%). After adjusting for covariates, living with spouse only was associated with lower odds of SCD-plus (odds ratio [OR]\u2009=\u20090.72, 95% confidence interval [CI] [0.55, 0.95]) compared to living alone. Frequent NSI was linked to lower odds of SCD-plus (OR\u2009=\u20090.65, 95% CI [0.54, 0.80]) and reduced feature scores (regression coefficient [\u03b2]\u2009=\u2009\u22120.16, 95% CI [\u22120.25, \u22120.07]). Compared to living alone \u2013 no NSI, all other combinations showed better SCD-plus status, especially living with spouse only with frequent NSI, which demonstrated a 55% reduction in likelihood (OR\u2009=\u20090.45, 95% CI [0.28, 0.73]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Living with spouse only and frequent NSI significantly lowers the odds of SCD-plus, providing a basis for further exploration of the impact of social interactions on cognitive health.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877251322805","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T16:31:27Z","timestamp":1742574687000},"page":"1125-1135","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association between home dwelling situations, neighborhood 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