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This article explores the ethical implications of psychological responses known as self-fulfilling prophecies that may impact cognitive decline among individuals diagnosed with or at risk for AD. We describe questions these potential effects raise about the ways clinicians communicate with patients, as well as how caregivers may interact with patients. Recent advancements in biomarkers and treatment for AD underscore the urgency of understanding these phenomena and developing appropriate responses.<\/jats:p>","DOI":"10.1177\/13872877251331236","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T03:30:41Z","timestamp":1745206241000},"page":"736-739","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Dilemmas in diagnosing Alzheimer's disease: The peril and promise of self-fulfilling prophecies"],"prefix":"10.1177","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1299-9803","authenticated-orcid":false,"given":"Janet","family":"Malek","sequence":"first","affiliation":[{"name":"Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1183-0672","authenticated-orcid":false,"given":"Ariel","family":"Levchenko","sequence":"additional","affiliation":[{"name":"Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0487-304X","authenticated-orcid":false,"given":"Jill O","family":"Robinson","sequence":"additional","affiliation":[{"name":"Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3637-8526","authenticated-orcid":false,"given":"Jamie","family":"Fong","sequence":"additional","affiliation":[{"name":"Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9607-974X","authenticated-orcid":false,"given":"Chi-Ying R","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Neurology, Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7753-0331","authenticated-orcid":false,"given":"George R","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Neurology, Baylor College of Medicine, Houston, TX, USA"},{"name":"Center for Alzheimer's and Neurodegenerative Diseases, Baylor College of Medicine, Houston, TX, USA"},{"name":"Parkinson's Disease Research, Education, and Clinical Center, Michael E. 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