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Phthalate and bisphenol exposure did not show association of individual urinary biomarkers with A\u03b2 or clinical phenotype (mild cognitive impairment (MCI)\/AD). Assessing biomarkers in quartiles, low mono(2-ethylhexyl) phthalate (MEHP), but not other biomarkers of di(2-ethylhexyl) phthalate (DEHP), was associated with A\u03b2+ and with having MCI\/AD (q\u2009&lt;\u20090.05), while high Bisphenol S (BPS) was associated with A\u03b2+ (q\u2009&lt;\u20090.05). Mixture analysis shows significant association with MCI\/AD but not A\u03b2.<\/jats:p>","DOI":"10.1177\/13872877251364559","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T05:23:28Z","timestamp":1754285008000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association of plastic-associated chemicals with Alzheimer's disease amyloid-\u03b2 and cognitive status"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3987-8884","authenticated-orcid":false,"given":"Rodrigo","family":"Canovas","sequence":"first","affiliation":[{"name":"The Australian E-Health Research Centre, CSIRO, Parkville, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2863-0293","authenticated-orcid":false,"given":"James D","family":"Doecke","sequence":"additional","affiliation":[{"name":"The Australian E-Health Research Centre, CSIRO, Herston, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1397-0359","authenticated-orcid":false,"given":"Christopher J","family":"Fowler","sequence":"additional","affiliation":[{"name":"The Florey Institute, The University of Melbourne, Parkville, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9705-0079","authenticated-orcid":false,"given":"Jurgen","family":"Fripp","sequence":"additional","affiliation":[{"name":"The Australian E-Health Research Centre, CSIRO, Herston, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5917-3366","authenticated-orcid":false,"given":"Xianyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD, Australia"},{"name":"Minderoo Centre \u2013 Plastics and Human Health, Woolloongabba, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen F","family":"Mueller","sequence":"additional","affiliation":[{"name":"Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD, Australia"},{"name":"Minderoo Centre \u2013 Plastics and Human Health, Woolloongabba, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9686-3630","authenticated-orcid":false,"given":"Ayomi","family":"Jayarathne","sequence":"additional","affiliation":[{"name":"Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD, Australia"},{"name":"Minderoo Centre \u2013 Plastics and Human Health, Woolloongabba, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2345-5940","authenticated-orcid":false,"given":"Chang","family":"He","sequence":"additional","affiliation":[{"name":"Queensland Alliance for Environmental Health Sciences (QAEHS), The University of Queensland, Woolloongabba, QLD, Australia"},{"name":"Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, P. 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