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Nationally-representative estimates of the proportion of dementia prevalence associated with sensory risk factors in late-life are needed for dementia prevention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To estimate the fraction of dementia prevalence associated with treatable sensory risk factors (hearing and vision loss) and to evaluate differences by age, race\/ethnicity, income, and sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross-sectional analysis of Round 12 (2022) of the National Health and Aging Trends Study, a population-based study nationally representative of US Medicare beneficiaries. Among community-living adults aged \u226565 years eligible for cognitive, hearing, and vision assessments (n\u2009=\u20094623), the summary population attributable fraction (PAF) of dementia from at least one objectively-measured sensory risk factor was estimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of at least one sensory risk factor was 66% and dementia was 9%. The PAF of dementia from at least one sensory risk factor was 57% (95% CI: 8%\u201361%). PAFs were larger for individuals who were aged &lt;80 years compared to \u226580 years (59% [95% CI: 42%\u201374%] versus 33% [95% CI: \u22126%\u201368%), non-Hispanic White compared to Hispanic and non-Hispanic Black (63% [95% CI: 41%\u201380%] versus 50% [95% CI: 16%\u201380%] and 32% [95% CI: \u22121%\u201364%]), and had higher income versus lower income (57% [95% CI: 36%\u201374%] versus 47% [95% CI: 7%\u201381%]). PAFs were consistent by sex.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Up to 57% of dementia prevalence in the US was associated with clinically-significant sensory risk factors. Addressing sensory impairments could play an important role in national dementia risk reduction strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877251386439","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T17:21:59Z","timestamp":1760721719000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Summary population attributable fraction of dementia prevalence associated with sensory risk factors"],"prefix":"10.1177","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9764-5849","authenticated-orcid":false,"given":"Jason R","family":"Smith","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"},{"name":"Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"},{"name":"Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wuyang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"},{"name":"Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel E","family":"Garcia Morales","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"},{"name":"Cochlear Center for 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Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Ramulu","sequence":"additional","affiliation":[{"name":"Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather E","family":"Whitson","sequence":"additional","affiliation":[{"name":"Department of Medicine and the Aging Center, Duke University School of Medicine, Durham, NC, USA"},{"name":"Geriatric Research Education and Clinical Center, Durham VA Health Care System, Durham, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Martinez-Amezcua","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA"},{"name":"Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 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