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Biomarker levels were measured in baseline samples of serum (glial fibrillary acid protein, neurofilament light chain (NfL), phosphorylated tau181; n\u2009=\u2009363) or plasma (amyloid-\u03b2\n                    <jats:sub>42\/40<\/jats:sub>\n                    -ratio, total-tau; n\u2009=\u2009232). Cognitive scores and MCI were measured at ten-year follow-up using the Cognitive Telephone Screening Instrument. At follow-up, 14.7% had MCI. The amyloid-\u03b2\n                    <jats:sub>42\/40<\/jats:sub>\n                    -ratio was predictive of cognitive scores, while NfL was associated with increased risk of MCI, suggesting that these biomarkers might be utilized for risk stratification.\n                  <\/jats:p>","DOI":"10.1177\/13872877251389147","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T17:52:36Z","timestamp":1763488356000},"page":"1507-1513","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prospective associations of blood-based biomarkers of neurodegenerative diseases with cognitive performance in a cohort of patients with chronic coronary syndrome"],"prefix":"10.1177","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5589-9701","authenticated-orcid":false,"given":"Valerie","family":"Lohner","sequence":"first","affiliation":[{"name":"Cardiovascular Epidemiology of Aging, Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Perna","sequence":"additional","affiliation":[{"name":"Department Genes and Environment, Max Planck Institute of Psychiatry, Munich, Germany"},{"name":"Division of Mental Health of Older Adults, Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Sch\u00f6ttker","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology of Early Detection, German Cancer Research Center (DKFZ), Heidelberg, Germany"},{"name":"Network Aging Research, Heidelberg University, Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Perneczky","sequence":"additional","affiliation":[{"name":"Division of Mental Health of Older Adults, Department of Psychiatry and Psychotherapy, LMU Hospital, LMU Munich, Munich, Germany"},{"name":"Ageing Epidemiology (AGE) Research Unit, School of Public Health, Imperial College London, White City Campus, London, UK"},{"name":"German Center for Neurodegenerative Diseases (DZNE), Munich, Germany"},{"name":"Munich Cluster for Systems Neurology (SyNergy), Munich, Germany"},{"name":"Sheffield Institute for Translational Neurology (SITraN), University of Sheffield, Sheffield, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Kliegel","sequence":"additional","affiliation":[{"name":"Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Brenner","sequence":"additional","affiliation":[{"name":"Network Aging Research, Heidelberg University, Heidelberg, Germany"},{"name":"Cancer Prevention Graduate School, German Cancer Research Center (DKFZ), Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ute","family":"Mons","sequence":"additional","affiliation":[{"name":"Cardiovascular Epidemiology of Aging, Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany"},{"name":"Division of Primary Cancer Prevention, German Cancer Research Center (DKFZ), Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019","volume":"7","author":"GBD 2019 Dementia Forecasting Collaborators","year":"2022","unstructured":"GBD 2019 Dementia Forecasting Collaborators. 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