{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:17:09Z","timestamp":1793906229159,"version":"4.8.0"},"reference-count":114,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder marked by progressive cognitive decline, functional impairment, and ultimately, loss of independence. Traditional models centered on amyloid-\u03b2 and tau pathology have expanded to encompass interconnected processes such as neuroinflammation, synaptic dysfunction, and gut\u2013brain axis disruption, underscoring the multifactorial nature of the disease. In this review, we delivered that advances in diagnosis now integrate fluid biomarkers within the A\/T\/N\/X framework, high-resolution neuroimaging, and artificial intelligence, enabling earlier and more precise disease characterization. On the therapeutic front, the approval of anti-amyloid monoclonal antibodies marks a paradigm shift toward disease-modifying approaches, yet challenges remain regarding efficacy, safety, and accessibility. Complementary strategies, including cognitive interventions and innovative drug delivery systems, highlight the need for multidimensional care that extends beyond pharmacology to improve patient quality of life. Furthermore, emerging avenues such as stem cell therapy, multitarget drug development, and precision medicine approaches illustrate a field in transition\u2014shifting from symptomatic management toward personalized strategies aimed at altering the course of AD.<\/jats:p>","DOI":"10.1177\/13872877251391820","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:58:24Z","timestamp":1761757104000},"page":"17-33","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Alzheimer's disease diagnosis and treatment: From pathophysiological insights to therapeutic advances in the era of precision neurology (2025 review)"],"prefix":"10.1177","volume":"109","author":[{"given":"Maru","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, College of Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyemin","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology, College of Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seoyeon","family":"Sohn","sequence":"additional","affiliation":[{"name":"Department of Neurology, College of Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woong Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology, College of Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9478-4998","authenticated-orcid":false,"given":"Kyoungjoo","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Life Science, Kyonggi University, Suwon, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyung Whan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology, College of Medicine, Yonsei University, Seoul, South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2024.1429211"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-024-00432-x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02505-2"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01249-0"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12202"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2020.600084"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.332127"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25071659"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1304839"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1705971"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30480-6"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212948"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2100708"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201606210"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-5949.2010.00177.x"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-025-00835-z"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)70016-5"},{"key":"e_1_3_3_19_2","first-page":"321","article-title":"Neuroinflammation in Alzheimer disease","author":"Heneka MT","unstructured":"Heneka MT, van der Flier WM, Jessen F, et al. Neuroinflammation in Alzheimer disease. Nat Rev Immunol 2025; 25: 321\u2013352.","journal-title":"Nat Rev Immunol"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-017-0733-2"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41583-018-0067-3"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2023.05.031"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.14348\/molcells.2017.0096"},{"key":"e_1_3_3_24_2","first-page":"1512","article-title":"Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people","volume":"70","author":"Wirth M","year":"2013","unstructured":"Wirth M, Villeneuve S, Haase CM, et al. Associations between Alzheimer disease biomarkers, neurodegeneration, and cognition in cognitively normal older people. JAMA Neurol 2013; 70: 1512\u20131519.","journal-title":"JAMA Neurol"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2016.6117"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad267"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1149618"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116601"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S350939"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/alz.12683"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100480050002"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2011.96"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000110315.26026.EF"},{"key":"e_1_3_3_34_2","first-page":"606802","article-title":"CSF Biomarkers for Alzheimer\u2019s disease diagnosis","volume":"2010","author":"Anoop A","year":"2010","unstructured":"Anoop A, Singh PK, Jacob RS, et al. CSF Biomarkers for Alzheimer\u2019s disease diagnosis. Int J Alzheimers Dis 2010; 2010: 606802.","journal-title":"Int J Alzheimers Dis"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-017-0073-9"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03617-7"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03565-2"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-020-02215-w"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-022-00750-6"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.3390\/make6010024"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s44220-024-00237-x"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e39217"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy132"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.2174\/1871527322666230627123426"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2023.105192"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25189936"},{"key":"e_1_3_3_47_2","article-title":"Comparative study of choline alfoscerate as a combination therapy with donepezil: a mixed double-blind randomized controlled and open-label observation trial","volume":"103","author":"Lee W","year":"2024","unstructured":"Lee W, Kim M. Comparative study of choline alfoscerate as a combination therapy with donepezil: a mixed double-blind randomized controlled and open-label observation trial. Medicine (Baltimore) 2024; 103: e38067.","journal-title":"Medicine (Baltimore)"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-024-05531-y"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-80102-0"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnimg.2024.1358221"},{"key":"e_1_3_3_51_2","article-title":"Evaluating the efficacy and safety of Alzheimer's disease drugs: a meta-analysis and systematic review","volume":"103","author":"Chen Y","year":"2024","unstructured":"Chen Y, Lai M, Tao M. Evaluating the efficacy and safety of Alzheimer's disease drugs: a meta-analysis and systematic review. Medicine (Baltimore) 2024; 103: e37799.","journal-title":"Medicine (Baltimore)"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.1.3.527"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2024.1398952"},{"key":"e_1_3_3_54_2","first-page":"303","article-title":"Donepezil in Alzheimer's disease: from conventional trials to pharmacogenetics","volume":"3","author":"Cacabelos R","year":"2007","unstructured":"Cacabelos R. Donepezil in Alzheimer's disease: from conventional trials to pharmacogenetics. Neuropsychiatr Dis Treat 2007; 3: 303\u2013333.","journal-title":"Neuropsychiatr Dis Treat"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21103438"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2002.tb11294.x"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trci.2019.09.011"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2005.09.007"},{"key":"e_1_3_3_59_2","article-title":"Effect of long-term treatment with memantine on mortality in patients with major cognitive disorders: a systematic review and meta-analysis","volume":"11","author":"Zolnowski-Kolp V","year":"2025","unstructured":"Zolnowski-Kolp V, Oquendo B, Havreng-Th\u00e9ry C, et al. Effect of long-term treatment with memantine on mortality in patients with major cognitive disorders: a systematic review and meta-analysis. Alzheimers Dement (N Y) 2025; 11: e70071.","journal-title":"Alzheimers Dement (N Y)"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.21699"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/s43856-024-00527-6"},{"key":"e_1_3_3_62_2","first-page":"1","article-title":"Safety issues of donepezil combined with memantine in Alzheimer\u2019s disease population: real-world pharmacovigilance","author":"Zeng Y","unstructured":"Zeng Y, Liu B, Zhou L, et al. Safety issues of donepezil combined with memantine in Alzheimer\u2019s disease population: real-world pharmacovigilance. Expert Opin Drug Safety 2025; 24: 1\u201311.","journal-title":"Expert Opin Drug Safety"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1439115"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-10-57"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.45878"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.4140\/TCP.n.2023.300"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-220530"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2024.2355981"},{"key":"e_1_3_3_69_2","first-page":"1077","article-title":"Donepezil-loaded nanocarriers for the treatment of Alzheimer\u2019s disease: superior efficacy of extracellular vesicles over polymeric nanoparticles","author":"Oliveira Silva R","unstructured":"Oliveira Silva R, Counil H, Rabanel J-M, et al. Donepezil-loaded nanocarriers for the treatment of Alzheimer\u2019s disease: superior efficacy of extracellular vesicles over polymeric nanoparticles. Int J Nanomed 2024; 19: 1077\u20131096.","journal-title":"Int J Nanomed"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-95792-3"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e37702"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-024-01636-3"},{"key":"e_1_3_3_73_2","first-page":"1934","article-title":"Nose-to-brain targeted delivery of donepezil hydrochloride via novel hyaluronic acid-doped nanotransfersomes for Alzheimer's disease mitigation","volume":"113","author":"Salem HF","year":"2024","unstructured":"Salem HF, Aboud HM, Abdellatif MM, et al. Nose-to-brain targeted delivery of donepezil hydrochloride via novel hyaluronic acid-doped nanotransfersomes for Alzheimer's disease mitigation. J Pharm Sci 2024; 113: 1934\u20131945.","journal-title":"J Pharm Sci"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2021.102549"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.13681"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2025.e00570"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.3348\/jksr.2024.0146"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1399121"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-022-01124-2"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-023-00633-2"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2025.2500752"},{"key":"e_1_3_3_82_2","article-title":"APOLLOE4 Phase 3 study of oral ALZ-801\/valiltramiprosate in APOE \u03b54\/\u03b54 homozygotes with early Alzheimer's disease: trial design and baseline characteristics","volume":"10","author":"Abushakra S","year":"2024","unstructured":"Abushakra S, Porsteinsson AP, Sabbagh M, et al. APOLLOE4 Phase 3 study of oral ALZ-801\/valiltramiprosate in APOE \u03b54\/\u03b54 homozygotes with early Alzheimer's disease: trial design and baseline characteristics. Alzheimers Dement (N Y) 2024; 10: e12498.","journal-title":"Alzheimers Dement (N Y)"},{"key":"e_1_3_3_83_2","first-page":"407","article-title":"Clinical pharmacokinetics of oral ALZ-801\/valiltramiprosate in a 2-year phase 2 trial of APOE4 carriers with early Alzheimer\u2019s disease","volume":"64","author":"Hey JA","year":"2025","unstructured":"Hey JA, Yu JY, Abushakra S, et al. Clinical pharmacokinetics of oral ALZ-801\/valiltramiprosate in a 2-year phase 2 trial of APOE4 carriers with early Alzheimer\u2019s disease. Clin Pharmacokinet 2025; 64: 407\u2013424.","journal-title":"Clin Pharmacokinet"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2024.08.005"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2024.3937"},{"key":"e_1_3_3_86_2","article-title":"ARIA In patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease","volume":"9","author":"Honig LS","year":"2023","unstructured":"Honig LS, Barakos J, Dhadda S, et al. ARIA In patients treated with lecanemab (BAN2401) in a phase 2 study in early Alzheimer's disease. Alzheimers Dement (N Y) 2023; 9: e12377.","journal-title":"Alzheimers Dement (N Y)"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01911-3"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-024-02691-6"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2025.e00591"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28083588"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202401629"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13113098"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2024.1465871"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.31083\/JIN25368"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2025.120236"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03565-2"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12017-025-08857-x"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-020-0884-2"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1002\/alz.082752"},{"key":"e_1_3_3_100_2","article-title":"Beyond lecanemab: examining Phase III potential in Alzheimer's therapeutics","volume":"3","author":"Osaka H","year":"2024","unstructured":"Osaka H, Nishida K, Kanazawa T. Beyond lecanemab: examining Phase III potential in Alzheimer's therapeutics. Psychiatry Clin Neurosci Rep 2024; 3: e185.","journal-title":"Psychiatry Clin Neurosci Rep"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1002\/alz.094677"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2009-1092"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2024.05.005"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12868-024-00920-w"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.29090\/psa.2024.01.23.1061"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-024-01118-y"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10040573"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.3390\/cimb47030148"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1038\/s44400-025-00011-5"},{"key":"e_1_3_3_110_2","article-title":"The latest advances in the diagnosis and treatment of dementia","volume":"15","author":"Hafiz R","year":"2023","unstructured":"Hafiz R, Alajlani L, Ali A, et al. The latest advances in the diagnosis and treatment of dementia. Cureus 2023; 15: e50522.","journal-title":"Cureus"},{"key":"e_1_3_3_111_2","article-title":"Cognitive stimulation to improve cognitive functioning in people with dementia","volume":"1","author":"Woods B","year":"2023","unstructured":"Woods B, Rai HK, Elliott E, et al. Cognitive stimulation to improve cognitive functioning in people with dementia. Cochrane Database Syst Rev 2023; 1: CD005562.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.3310\/hta23100"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1481678"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-018-2988-6"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-79039-1"}],"container-title":["Journal of Alzheimer\u2019s Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13872877251391820","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/13872877251391820","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/13872877251391820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:09:32Z","timestamp":1777370972000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/13872877251391820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,29]]},"references-count":114,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/13872877251391820"],"URL":"https:\/\/doi.org\/10.1177\/13872877251391820","relation":{},"ISSN":["1387-2877","1875-8908"],"issn-type":[{"value":"1387-2877","type":"print"},{"value":"1875-8908","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,29]]}}}