{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T12:11:59Z","timestamp":1783944719528,"version":"3.55.0"},"reference-count":58,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Katherine Rankin","award":["P01 AG019724"],"award-info":[{"award-number":["P01 AG019724"]}]},{"name":"Katherine Rankin","award":["P30 AG062422"],"award-info":[{"award-number":["P30 AG062422"]}]},{"name":"Katherine Rankin","award":["P50 AG023501"],"award-info":[{"award-number":["P50 AG023501"]}]},{"name":"Katherine Rankin","award":["RF1 AG029577"],"award-info":[{"award-number":["RF1 AG029577"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Depression assessment in persons with dementia (PWD) often prioritizes caregiver report, with limited integration of self-report due to concerns about PWD insight.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This cross-sectional study examined discrepancies between self- and caregiver-reported depression in PWD and identified neuropsychiatric and diagnostic predictors of discordance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>402 PWD diagnosed with Alzheimer's disease (AD), behavioral variant frontotemporal dementia (bvFTD), semantic variant primary progressive aphasia (svPPA), or progressive supranuclear palsy (PSP) self-reported depression using the Geriatric Depression Scale (GDS), while caregivers completed the Neuropsychiatric Inventory (NPI). Discrepancies were categorized as Concordant (agreement), Discordant Type 1 (self-reported depression denied by caregiver), or Discordant Type 2 (caregiver-reported depression denied by PWD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One-third (33.8%) of dyads showed discrepancies: 66.2% were concordant, 10.2% Discordant Type 1, and 23.6% Discordant Type 2. PSPs had higher incidence of Type 1 discordance compared to AD (OR\u2009=\u20092.91, p\u2009&lt;\u20090.05), while svPPAs were less likely to incur Type 2 discordance than AD (OR\u2009=\u20090.33, p\u2009&lt;\u20090.01). Higher self-reported GDS Hopelessness, Withdrawal, and Worry predicted higher rates of Type 1 discordance, while lower Dysphoria predicted Type 2 discordance. Higher caregiver-reported NPI Apathy increased odds of Type 1 discordance (OR\u2009=\u20092.46, p\u2009&lt;\u20090.05) and lower NPI Anxiety increased odds of Type 2 discordance (OR\u2009=\u20090.50, p\u2009&lt;\u20090.01). Among cases with Type 1 discordance, caregivers often endorsed PWD apathy, irritability, agitation, or anxiety instead of depression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Discrepancies in reporting depression in PWD can reflect underreporting by caregivers, not only denial by PWD. Integrating self-report, caregiver input, and clinical judgment may improve diagnostic accuracy for depression in PWD and improve care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261422511","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T13:58:38Z","timestamp":1773669518000},"page":"1315-1327","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling discrepancies in depression detection among persons with dementia: A comparative analysis of caregiver and self-report"],"prefix":"10.1177","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1144-380X","authenticated-orcid":false,"given":"Bailey L.","family":"Ortiz","sequence":"first","affiliation":[{"name":"University of California, San Francisco"},{"name":"Palo Alto University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron 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