{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T15:18:11Z","timestamp":1778167091210,"version":"3.51.4"},"reference-count":74,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Projet Hospitalier de Recherche Clinique (PHRC) inter-r\u00e9gional","award":["IDRCB 2012-A00992-41"],"award-info":[{"award-number":["IDRCB 2012-A00992-41"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>While language impairments are well-documented in Alzheimer's disease (AD), their longitudinal progression in dementia with Lewy bodies (DLB) remains poorly understood.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare four-year trajectories of naming and verbal fluency in DLB, AD, and healthy controls (HC), and to identify the cognitive correlates underlying naming performance over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study included 111 participants (62 DLB, 26 AD, 23 HC) followed at baseline, 12, 24, and 48 months. Primary outcomes were naming (DO-80) and verbal fluency (letter\/semantic) scores. Secondary assessments included verbal memory, executive, and visuospatial functions. Linear Mixed Models compared longitudinal trajectories, and Spearman correlations explored cognitive associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A significant Visit x Group interaction (p\u2009&lt;\u20090.001) revealed that naming remained stable in DLB (\u22121.15 points) and HC, whereas AD patients showed a steep decline (\u22127.77 points). In DLB, letter fluency remained stable over 48 months, while semantic fluency significantly decreased (p\u2009=\u20090.002). Conversely, AD patients deteriorated across all tasks. By month 48, DLB patients significantly outperformed AD patients in naming (p\u2009=\u20090.002) and semantic fluency (p\u2009=\u20090.015). Naming in DLB was positively and increasingly correlated with executive functions (Frontal Assessment Battery: rho 0.416 to 0.578) and Mini-Mental State Examination, whereas in AD, it was tied to episodic memory. No correlation was found with attentional fluctuations in DLB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings highlight distinct language trajectories: naming abilities are relatively preserved in DLB compared to the global collapse in AD. This preservation in DLB appears increasingly dependent on executive control, underscoring the need for tailored, domain-specific interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261427500","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:06:00Z","timestamp":1774533960000},"page":"1870-1885","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Language performances in dementia with Lewy bodies and Alzheimer's disease: A longitudinal comparative study of naming and fluency"],"prefix":"10.1177","volume":"110","author":[{"given":"Florence","family":"Labern\u00e8de","sequence":"first","affiliation":[{"name":"CM2R (Research and Resources Memory Centre), Geriatric Day Hospital, Geriatrics Division, University Hospitals of Strasbourg, Strasbourg, France"},{"name":"University of 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