{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:14:07Z","timestamp":1783415647027,"version":"3.54.6"},"reference-count":50,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dementia represents a major global health challenge, particularly in low- and middle-income countries (LMICs). Morocco, facing rapid population ageing, lacks integrated epidemiological and translational research on Alzheimer's disease (AD) and related disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to map Moroccan dementia studies and identify national advances and research gaps.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA-ScR guidelines, a literature search was conducted in PubMed, Scopus, MEDLINE, and Web of Science covering the period 2000\u20132025. Studies including Moroccan samples and addressing dementia or AD in epidemiology, diagnostics, genetics, or therapy were retained. Thirty papers met criteria. Data were summarized narratively and organized in four thematic tables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Moroccan research spans four main pillars: (1) early-onset and clinical features; (2) validated cognitive assessment tools adapted to Arabic and Tamazight; (3) discovery of distinct APP, PSEN, and APOE mutations; and (4) emerging pharmacological and non-pharmacological interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Though still limited, Moroccan dementia research demonstrates scientific maturity and regional relevance. Establishing national registries, biobanks, and culturally tailored interventions will strengthen Africa's contribution to global neurodegenerative research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261430304","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T10:26:07Z","timestamp":1773224767000},"page":"63-72","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mapping dementia research in Morocco: A scoping review of epidemiological, genetic, and therapeutic evidence"],"prefix":"10.1177","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9111-5879","authenticated-orcid":false,"given":"Youssef","family":"Razouqi","sequence":"first","affiliation":[{"name":"Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco"},{"name":"Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Casablanca, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0884-7794","authenticated-orcid":false,"given":"Hassan","family":"El-Abid","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-8432","authenticated-orcid":false,"given":"Loubna","family":"Khalki","sequence":"additional","affiliation":[{"name":"Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco"},{"name":"Interdisciplinary Laboratory of Biotechnology and Health, Neurosciences and Cellular Physiology Team, Mohammed VI Higher Institute of Biosciences and Biotechnology, Casablanca, Morocco"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.5535\/arm.22027"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2023.08.005"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-240650"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.32394\/rpzh.2022.0224"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/23279095.2022.2119143"},{"key":"e_1_3_3_7_2","article-title":"Cross-cultural adaptation and psychometric validation of the Moroccan dialect version of the zarit scale of dementia Caregivers\u2019 burden","volume":"19","author":"Ougjij AA","year":"2022","unstructured":"Ougjij AA, Achbani A, Chigr F. 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