{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T09:14:09Z","timestamp":1783415649611,"version":"3.54.6"},"reference-count":41,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Otsuka Pharmaceutical Co., Ltd., Tokyo, Japan","award":["NA"],"award-info":[{"award-number":["NA"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Agitation is a common behavioral and psychological symptom of dementia that places significant burden on caregivers. While its impact on family caregivers is well-documented, its effect on professional caregivers remains underexplored. Additionally, it is unclear whether existing caregiver burden scales adequately capture the International Psychogeriatric Association's (IPA) definition of agitation. Since agitation requires different treatment approaches than cognitive impairment, its distinct burden warrants further investigation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This systematic review examined scales used to assess professional caregiver burden related to agitation in dementia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA guidelines, we searched MEDLINE, Embase, and ICHUSHI for English and Japanese articles published during January 1980\u2013August 2024. Studies included professional caregivers, either exclusively or alongside informal caregivers. Key outcomes were the number and frequency of scales, target population, and agitation coverage within the scales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 52 articles: 22 focused exclusively on professional caregivers, and 30 included both types. Publications involving both caregiver types increased notably in the last decade. Across studies, 39 scales were used. The Zarit Burden Interview (n\u2009=\u200921) and Neuropsychiatric Inventory (n\u2009=\u200915) were most frequent. Sixteen scales targeted the general population; 11 each were designed for professional and informal caregivers, and one for both. Most scales did not fully reflect the IPA's definition of agitation. Scales for professional caregivers also included work-related factors like coworker conflicts and administrative workload.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There is a critical gap in validated scales to measure agitation-related burden in professional dementia caregivers. Specialized tools are urgently needed to assess this burden and guide support strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261430767","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:51:07Z","timestamp":1773665467000},"page":"115-124","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing professional caregiver burden related to patient agitation in dementia: A systematic review of measurement scales"],"prefix":"10.1177","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6395-5275","authenticated-orcid":false,"given":"Keisuke","family":"Onuki","sequence":"first","affiliation":[{"name":"Otsuka Pharmaceutical Co., Ltd"},{"name":"Department of Public Health, Graduate School of Medicine, Juntendo University, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6857-1200","authenticated-orcid":false,"given":"Yoshiyuki","family":"Nishio","sequence":"additional","affiliation":[{"name":"United Graduate School of Child Development, Osaka University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 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The Effects of Caregiver Turnover and Health Outcomes of Dementia Within Cedarbrook Memory Care, Fresno, California. Fresno, CA, USA: California State University, 2023."},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12912-025-03996-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00391-015-1002-0"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-023-04234-0"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1590\/1980-5764-dn-2022-0017"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-18470-8"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-230972"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1515\/med-2020-0124"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1080\/13607869956208"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","unstructured":"Aranco N Ibarrar\u00e1n P Stampini M. 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