{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:07:34Z","timestamp":1780391254034,"version":"3.54.1"},"reference-count":31,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dementia with Lewy bodies (DLB) remains underdiagnosed due to overlapping clinical features with Alzheimer's disease (AD) and vascular cognitive impairment (VCI). Early recognition is crucial, as DLB has distinct prognostic and therapeutic implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to develop and validate a brief, clinically applicable screening instrument to improve bedside recognition of DLB and to compare its performance with established diagnostic approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We designed the Dementia with Lewy Bodies Clinical Screening Questionnaire (DLBCSQ) and an extended version (DLBCSQ11) incorporating additional items to differentiate DLB from VCI. Clinical data were collected from a dementia registry in Taiwan, including patients with AD, VCI, and DLB. The diagnostic accuracy of DLBCSQ versions was evaluated using receiver operating characteristic (ROC) analyses across subgroups, including mild cognitive impairment with Lewy bodies (LB-MCI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both DLBCSQ and DLBCSQ11 demonstrated strong discriminatory ability, with area under the curve (AUC) values exceeding 0.84 for differentiating DLB from non-DLB syndromes. DLBCSQ11 showed greater specificity for distinguishing DLB from VCI, though about 20% of VCI patients still exhibited DLB-like features. Supplementary questions on visual hallucinations and tremors further improved detection of prodromal or mixed DLB cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The DLBCSQ9 and DLBCSQ11 represent practical and effective tools for clinical and bedside identification of DLB. By improving early recognition and differentiation from AD and VCI, these instruments may facilitate timely diagnosis, guide treatment decisions, and support future research on mixed dementia syndromes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261441187","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T15:35:48Z","timestamp":1776267348000},"page":"1073-1083","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Dementia with Lewy bodies clinical syndrome (DLBCS) questionnaire: A simple tool for the clinical screening of DLB"],"prefix":"10.1177","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2552-4516","authenticated-orcid":false,"given":"Pai-Yi","family":"Chiu","sequence":"first","affiliation":[{"name":"Show Chwan Memorial Hospital"},{"name":"Tunghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7955-1191","authenticated-orcid":false,"given":"Hung-Jui","family":"Chiu","sequence":"additional","affiliation":[{"name":"Tunghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Yu","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Exercise and Health Promotion, College of Kinesiology and Health, Chinese Culture University, Taipei, Taiwan"},{"name":"Department of Neurology, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray-Chang","family":"Tzeng","sequence":"additional","affiliation":[{"name":"Department of Neurology, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsin-Te","family":"Chang","sequence":"additional","affiliation":[{"name":"Tainan Municipal Hospital (Managed by Show Chwan Medical Care Corporation)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1478-4294","authenticated-orcid":false,"given":"Hong-Ming","family":"Chen","sequence":"additional","affiliation":[{"name":"Tunghai University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"The prevalence and incidence of dementia with Lewy bodies: a systematic review","volume":"43","author":"Hogan DB","year":"2016","unstructured":"Hogan DB, Fiest KM, Roberts JI, et al. The prevalence and incidence of dementia with Lewy bodies: a systematic review. 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