{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T16:31:27Z","timestamp":1786379487987,"version":"build-2736575974"},"reference-count":52,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Oligodendrocyte (OL) lineage biology is increasingly recognized as a contributor to Alzheimer's disease (AD) pathophysiology, but its global knowledge structure and emerging frontiers remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To map the development, major contributors, intellectual bases, and research frontiers of OL-related AD research using bibliometric and visualization approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>English-language articles and reviews published from 1990 to 2025 were retrieved from the Web of Science Core Collection on January 2, 2026. After deduplication, 1746 records were analyzed. VOSviewer 1.6.20 assessed publication output, contributors, collaborations, and citation networks. CiteSpace 6.1.6 performed keyword co-occurrence, clustering, and burst detection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Annual publications increased from 5 in 1990 to 149 in 2025, peaking at 154 in 2024, with acceleration after 2020. The United States led in productivity and impact (684 publications; 54,075 citations). Harvard University was the most productive institution (46 publications), whereas the University of California, Los Angeles had the highest average citation impact among leading institutions (147.20 citations per publication). Acta Neuropathologica was the most productive journal (66 publications; 6548 citations). Mathys et al. was the most influential cornerstone reference. Keyword clustering was robust (Q\u2009=\u20090.701, S\u2009=\u20090.958), identifying \u201cwhite matter\u201d as the central thematic cluster.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>OL-related AD research is expanding rapidly and shifting toward white matter-centered, cell state-resolved, and multi-omics paradigms. Future priorities include defining OL and oligodendrocyte precursor cell transcriptional states, clarifying myelin vulnerability and repair mechanisms, and linking OL pathology to amyloid-related processes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261456313","type":"journal-article","created":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T12:54:43Z","timestamp":1780404883000},"page":"1031-1044","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Global research landscape of oligodendrocytes in Alzheimer's disease: A bibliometric and knowledge-mapping analysis from 1990 to 2025"],"prefix":"10.1177","volume":"112","author":[{"given":"Jingyi","family":"Zhang","sequence":"first","affiliation":[{"name":"The Second Clinical Medical College, Heilongjiang University of Chinese Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Teng","sequence":"additional","affiliation":[{"name":"The Second Clinical Medical College, Heilongjiang University of Chinese Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Li","sequence":"additional","affiliation":[{"name":"Zaozhuang Hospital of Dongfang Hospital, Beijing University of Chinese Medicine, Zaozhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4421-7100","authenticated-orcid":false,"given":"Miao","family":"Zhang","sequence":"additional","affiliation":[{"name":"No. 10 Acupuncture Outpatient Department, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019","volume":"7","author":"GBD 2019 Dementia Forecasting Collaborators","year":"2022","unstructured":"GBD 2019 Dementia Forecasting Collaborators. 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