{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T16:31:25Z","timestamp":1786379485932,"version":"build-2736575974"},"reference-count":43,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neuropsychiatric symptoms (NPS) affect most individuals with Alzheimer's disease (AD) and are among the most burdensome aspects of the condition, negatively influencing caregivers\u2019 mental health, burden, and quality of care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Given the scarcity of studies examining caregivers\u2019 characteristics and NPS simultaneously, this study investigated how sociodemographic and clinical factors relate to different coping strategies, and whether NPS moderate these associations. Path analysis was used to capture direct and conditional effects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study of 176 caregiver\u2013patient dyads assessed coping, burden, mood, and NPS. Path analysis examined the effects of caregiver education, burden, depressive symptoms, and sex on coping, with NPS as a moderator.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Higher education predicted greater use of problem-focused (\u03b2\u2009=\u20090.43, p\u2009&lt;\u20090.001) and dysfunctional coping (\u03b2\u2009=\u20090.22, p\u2009&lt;\u20090.01). Burden was negatively linked to emotion-focused coping (\u03b2\u2009=\u2009\u22120.17, p\u2009&lt;\u20090.05). NPS moderated the burden\u2013problem-focused coping link (\u03b2\u2009=\u2009\u22120.16, p\u2009&lt;\u20090.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Education plays a central role in shaping how caregivers cope with care demands. NPS moderated the relationship between caregiver burden and problem-focused coping, with limited influence on other strategies. These findings underscore the importance of considering both caregiver characteristics and patient-related factors when developing interventions, highlighting the need for personalized approaches to improve caregiver well-being and care outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261458984","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T05:06:46Z","timestamp":1782277606000},"page":"1509-1518","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["When caring becomes a challenge: A path analysis of coping in Alzheimer's disease caregiving"],"prefix":"10.1177","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5112-4703","authenticated-orcid":false,"given":"Alexandre Magno Frota","family":"Monteiro","sequence":"first","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela Moreira","family":"Lima Nogueira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6284-3271","authenticated-orcid":false,"given":"Isabel","family":"Barbeito Lacerda","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Belfort","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6267-8202","authenticated-orcid":false,"given":"Marcia Cristina Nascimento","family":"Dourado","sequence":"additional","affiliation":[{"name":"Universidade Federal do Rio de Janeiro"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1263771"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2021.4363"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.877143"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.2019.195"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jagp.2024.06.005"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/13607863.2018.1531379"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-023-01279-6"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-200647"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12912-025-04014-8"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-025-06284-y"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-231259"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-215670"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/20.6.649"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-44462002000100006"},{"key":"e_1_3_3_16_2","article-title":"Remotely delivered information, training and support for informal caregivers of people with dementia","volume":"1","author":"Gonz\u00e1lez-Fraile E","year":"2021","unstructured":"Gonz\u00e1lez-Fraile E, Ballesteros J, Rueda JR, et al. 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