{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T09:11:45Z","timestamp":1789463505699,"version":"build-2803163510"},"reference-count":50,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["Project ID 456732630"],"award-info":[{"award-number":["Project ID 456732630"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Individuals with subjective cognitive decline (SCD) report declining cognitive abilities but do not have an objective cognitive impairment at present. Research indicates that they are at an elevated risk of developing Alzheimer's disease (AD). Identifying or developing cognitive measures capable of detecting cognitive deficits that individuals with SCD may experience is crucial, as they may benefit from additional diagnostic procedures and interventions aimed at delaying further cognitive decline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate whether specific cognitive tasks selected for their relevance in detecting early changes possibly related to AD can predict group membership SCD and Non-SCD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Neuropsychological assessment data of 73 older adults (35 SCD, 38 Non-SCD) was analyzed. Logistic regression analyses, classification metrics, and receiver operating characteristic curves were used to evaluate the predictive power of a model including a verbal fluency, word list learning, and constructional praxis test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Individuals with SCD were older and reported higher levels of depression. The logistic regression model demonstrated limited sensitivity (0.54) but high specificity (0.87). Constructional Praxis (visuo-spatial- and constructional abilities) emerged as a significant predictor (OR\u2009=\u20090.49, 95% CI: 0.26\u20130.86, p\u2009&lt;\u20090.05), even in an additional model controlling for affective symptoms. Better performance in this task was associated with lower odds of belonging to the SCD group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Existing cognitive assessments appear to lack sensitivity in the context of SCD. Visuo-cognitive functioning may represent a promising domain for the development of more sensitive diagnostic tools to detect possible cognitive alterations that individuals with SCD may experience.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261469875","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:06:06Z","timestamp":1785247566000},"page":"603-613","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Subtle visuo-cognitive deficits as a potential early marker of cognitive decline"],"prefix":"10.1177","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0462-8095","authenticated-orcid":false,"given":"Franziska","family":"Kiene","sequence":"first","affiliation":[{"name":"Ambulatory Assessment in Psychology, Department of Psychology, Carl von Ossietzky Universit\u00e4t Oldenburg, Oldenburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Becker","sequence":"additional","affiliation":[{"name":"Ambulatory Assessment in Psychology, Department of Psychology, Carl von Ossietzky Universit\u00e4t Oldenburg, Oldenburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Betten","sequence":"additional","affiliation":[{"name":"Ambulatory Assessment in Psychology, Department of Psychology, Carl von Ossietzky Universit\u00e4t Oldenburg, Oldenburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6015-3194","authenticated-orcid":false,"given":"Mandy","family":"Roheger","sequence":"additional","affiliation":[{"name":"Ambulatory Assessment in Psychology, Department of Psychology, Carl von Ossietzky Universit\u00e4t Oldenburg, Oldenburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2014.01.001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(19)30368-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.10.003"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13195-020-00734-y"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-150154"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03543.x"},{"key":"e_1_3_3_8_2","volume-title":"Neuropsychological Tools for Dementia: Differential Diagnosis and Treatment","author":"Hildebrandt H","year":"2021","unstructured":"Hildebrandt H. 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