{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T09:11:57Z","timestamp":1789463517421,"version":"build-2803163510"},"reference-count":38,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"European Union\u2019s INTERREG VA Programme","award":["CHI\/5431\/2018"],"award-info":[{"award-number":["CHI\/5431\/2018"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Alzheimer\u2019s Disease"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Individuals with type 2 diabetes mellitus (T2DM) face increased risk of cognitive decline and dementia. Multidomain lifestyle interventions offer a non-pharmacological strategy to support brain health in this high-risk group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the acceptability of a culturally adapted FINGER-based intervention among adults living with T2DM in rural border regions of Ireland (BRAIN-Diabetes Trial).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A 6-month pilot randomized controlled trial was conducted. The intervention group received a multidomain program targeting diet, physical activity, and computerized cognitive training (CCT). The control group received standard care. Acceptability was assessed using questionnaires (all participants) and semi-structured interviews (intervention participants). Quantitative data were analyzed descriptively and qualitative data using template analysis, guided by four a-priori themes: trial participation and engagement, dietary behavior change, exercise behavior change, and CCT behavior change.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Questionnaire data (intervention: n\u2009=\u200928; control: n\u2009=\u200936) indicated high overall acceptability. Dietary and exercise components were rated most positively, while CCT component was less well received. Interviews (n\u2009=\u200925) highlighted facilitators to trial engagement, including perceived health improvements, and social connection, with time constraints and limited personalization as barriers. Dietary change was supported by tailored guidance but hindered by cost and availability. Facilitators for exercise included accessible resources and perceived benefits, with barriers including competing priorities. CCT engagement was mixed, with challenges including digital access and repetitiveness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Brain-Diabetes intervention was acceptable and feasible among adults with T2DM. Personalized support and accessible resources were key to engagement. Future work should refine delivery to enhance scalability and long-term adherence among high-risk groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/13872877261471915","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:01:21Z","timestamp":1786629681000},"page":"945-958","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["BRAIN-Diabetes: Acceptability of an adapted FINGER multidomain intervention among adults living with type 2 diabetes in rural border regions across the island of Ireland"],"prefix":"10.1177","volume":"113","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8192-4794","authenticated-orcid":false,"given":"Rebecca F.","family":"Townsend","sequence":"first","affiliation":[{"name":"Newcastle University"},{"name":"Newcastle University"},{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lesley L.","family":"Hamill","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic N.","family":"Farsi","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"},{"name":"King's College London"},{"name":"Universit\u00e9 Clermont Auvergne"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"McCarthy","sequence":"additional","affiliation":[{"name":"National University of Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Dolan","sequence":"additional","affiliation":[{"name":"National University of Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"McGuinness","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean P.","family":"Kennelly","sequence":"additional","affiliation":[{"name":"Tallaght University Hospital"},{"name":"Trinity College Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Regan-Moriarty","sequence":"additional","affiliation":[{"name":"Atlantic Technological University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Kee","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Passmore","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayne V.","family":"Woodside","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"},{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire T.","family":"McEvoy","sequence":"additional","affiliation":[{"name":"Queen's University Belfast"},{"name":"Queen's University Belfast"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60461-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2014.14070878"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-016-4127-9"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2017.05.005"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-0120"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.13103"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/dme.15034"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10433-025-00862-0"},{"key":"e_1_3_3_10_2","article-title":"A new framework for developing and evaluating complex interventions: update of medical research council guidance","volume":"374","author":"Skivington K","year":"2021","unstructured":"Skivington K, Matthews L, Simpson SA, et al. 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