{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:52:24Z","timestamp":1777938744451,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scand J Surg"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>With the development of rapid assays and intraoperative measurement of intact parathyroid hormone (PTH), new strategies in the handling of patients with primary hyperparathyroidism (pHPT) have evolved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The aim of our study was to illustrate the performance of the intraoperative PTH measurement as a predictor of successful cure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods:<\/jats:title>\n                    <jats:p>From September 1999 to April 2002 143 patients with pHPT underwent a parathyroid operation (bilateral neck exploration with identification of all parathyroid glands) with intraoperative measurements of plasma PTH (immediately prior to surgery (T0) and 5 minutes after gland excision (T5)). A positive test result was defined as plasma PTH values at T5 below 20 % of T0 or a value in the normal range below 7.6 pmol\/l. Hence T5 values above 20 % of T0 and above 7.6 pmol\/l were considered test negative.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>122 patients (85 %) were test positive and cured, 11 patients (8 %) were test negative but cured, and 10 patients (7 %) were test negative and not cured by the primary operation. Consequently, the sensitivity of the test was 0.92 and the specificity 1.00.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The rapid PTH test used is a reliable predictor of a successful outcome in pHPT patients undergoing parathyroid surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/145749690409300109","type":"journal-article","created":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T11:41:04Z","timestamp":1500378064000},"page":"43-47","source":"Crossref","is-referenced-by-count":11,"title":["Primary Hyperparathyroidism: Intraoperative Pth-Measurements"],"prefix":"10.1177","volume":"93","author":[{"given":"L.","family":"Rolighed","sequence":"first","affiliation":[{"name":"Surgical Department L, Breast and Endocrine Section"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Heickendorff","sequence":"additional","affiliation":[{"name":"Department of Clinical Biochemistry"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Hessov","sequence":"additional","affiliation":[{"name":"Surgical Department L, Breast and Endocrine Section"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. P.","family":"Garne","sequence":"additional","affiliation":[{"name":"Surgical Department L, Breast and Endocrine Section"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. \u00c5.","family":"Rodt","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Aarhus Amtssygehus, Aarhus University Hospital, Aarhus, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Surgical Department L, Breast and Endocrine Section"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,3,1]]},"reference":[{"key":"bibr1-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2001.114556"},{"key":"bibr2-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2002.119817"},{"key":"bibr3-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-001-9013-x"},{"key":"bibr4-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-4001(00)00107-0"},{"key":"bibr5-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430220068015"},{"key":"bibr6-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.2.186"},{"key":"bibr7-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/46.10.1662"},{"key":"bibr8-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2099.101429"},{"key":"bibr9-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2099.101426"},{"key":"bibr10-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.83.11.5254"},{"key":"bibr11-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1007\/BF01658526"},{"key":"bibr12-145749690409300109","first-page":"E886","volume":"255","author":"Bringhurst FR","year":"1988","journal-title":"Am J Physiol"},{"key":"bibr13-145749690409300109","first-page":"1121","volume":"104","author":"Nussbaum SR","year":"1988","journal-title":"Surgery"},{"key":"bibr14-145749690409300109","first-page":"1035","volume":"110","author":"Proye CA","year":"1991","journal-title":"Surgery"},{"key":"bibr15-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90617-Y"},{"key":"bibr16-145749690409300109","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.3.8304"},{"key":"bibr17-145749690409300109","first-page":"3107","volume":"80","author":"Hosokawa Y","year":"1995","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Scandinavian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/145749690409300109","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/145749690409300109","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:50:00Z","timestamp":1777697400000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/145749690409300109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["10.1177\/145749690409300109"],"URL":"https:\/\/doi.org\/10.1177\/145749690409300109","relation":{},"ISSN":["1457-4969","1799-7267"],"issn-type":[{"value":"1457-4969","type":"print"},{"value":"1799-7267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}