{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:46:42Z","timestamp":1790660802689,"version":"4.1.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T00:00:00Z","timestamp":1530662400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scand J Surg"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Appendicitis is a common presentation to hospital with appendectomy being the treatment of choice. Pre-operative administration of broad-spectrum antibiotics is common, but obtaining intra-abdominal pus samples is not. After an initial 6-month retrospective audit and departmental teaching on the importance of intra-peritoneal pus sampling, we aimed to determine whether intra-operative pus samples changed antibiotic management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Following the initial audit cycle, a 6-month prospective cohort study was conducted. Clinical data were collected on a predetermined proforma to assess the effectiveness of the intervention and antibiotic prescribing practice. The data collected during the whole 1-year period was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>During the 1-year period, 440 patients were identified as undergoing a laparoscopic procedure. After exclusion, 261 patients were identified as undergoing laparoscopic appendectomies, of which 141 (54%) were classified as complicated laparoscopic appendectomies. A total of 35 out of 141 (25%) pus samples were sent of which 24 (17%) resulted in positive cultures, with only nine of these positive cultures reported prior to the patient being discharged. No patient had their antibiotic regimen changed as a result of the culture results. There were three cases of cultures resistant to local antibiotics, but without significant clinical outcome. One of these patients developed a post-operative complication, but the antibiotic regimen was changed to broad spectrum rather than a specific antibiotic based on culture sensitivity. Of the 141 patients with complicated laparoscopic appendectomies, five (3.5%) developed post-operative complications: one readmission requiring a laparoscopic washout for pelvic collection, three (2%) cases of pelvic collections managed conservatively, and one case of prolonged paralytic ileus managed non-operatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Overall, none of the patients with positive cultures had a change in prescribed antibiotics based on culture results. Hence, the routine practice of intra-peritoneal pus sampling following complicated appendicitis remains of little clinical value.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1457496918783721","type":"journal-article","created":{"date-parts":[[2018,7,5]],"date-time":"2018-07-05T01:30:50Z","timestamp":1530754250000},"page":"55-60","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Pus Samples in Complicated Appendicitis: An Important Investigation or a Waste of Resources: A Prospective Cohort Study"],"prefix":"10.1177","volume":"108","author":[{"given":"A. A.","family":"Akingboye","sequence":"first","affiliation":[{"name":"Department of General Surgery, Peterborough City Hospital, Peterborough, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Davies","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Peterborough City Hospital, Peterborough, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Tien","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Colchester Hospital University NHS Foundation Trust, Colchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,7,4]]},"reference":[{"key":"bibr1-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38940.664363.AE"},{"key":"bibr2-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2017-0048"},{"key":"bibr3-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1177\/1457496913497433"},{"key":"bibr4-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2006.00774.x"},{"key":"bibr5-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(99)90368-8"},{"key":"bibr6-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"bibr7-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2015.03.005"},{"key":"bibr8-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.11.003"},{"key":"bibr9-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.12.063"},{"key":"bibr10-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-013-1055-2"},{"key":"bibr11-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2008.06.006"},{"key":"bibr12-1457496918783721","first-page":"310","volume":"8","author":"Kenig J","year":"2013","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"bibr13-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1989.01410110034006"},{"key":"bibr14-1457496918783721","first-page":"278","volume":"6","author":"Foo FJ","year":"2008","journal-title":"Surg"},{"key":"bibr15-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-007-0003-4"},{"key":"bibr16-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1086\/649554"},{"key":"bibr17-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-009-2540-6"},{"key":"bibr18-1457496918783721","doi-asserted-by":"publisher","DOI":"10.1080\/110241501750099456"},{"key":"bibr19-1457496918783721","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1177\/000313480006600605","volume":"66","author":"Pittman-Waller VA","year":"2000","journal-title":"Am Surg"}],"container-title":["Scandinavian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1457496918783721","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1457496918783721","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1457496918783721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:56:37Z","timestamp":1777697797000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1457496918783721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,4]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1177\/1457496918783721"],"URL":"https:\/\/doi.org\/10.1177\/1457496918783721","relation":{},"ISSN":["1457-4969","1799-7267"],"issn-type":[{"value":"1457-4969","type":"print"},{"value":"1799-7267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,4]]}}}