{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:56:05Z","timestamp":1777938965012,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T00:00:00Z","timestamp":1589760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scand J Surg"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Endovascular aneurysm sealing represents an alternative to advanced technology devices for compromised patients with abdominal aortic aneurysms. We report our results of 15 fragile patients with very low-quality infrarenal necks treated with endovascular aneurysm sealing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods:<\/jats:title>\n                    <jats:p>All patients treated with Nellix device in our hospital between June 2015 and October 2016 were retrospectively reviewed. The primary endpoints are the following: overall survival and freedom from reintervention rates. The secondary endpoints are the following: technical success; 30-day mortality; abdominal aortic aneurysm\u2013related mortality; and freedom from endoleak rate, complications, and surgical conversion rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Nellix was used in 15 patients, median age 75.5\u2009years, of which 67% were unfit for open surgery. Mean aneurysm diameter was 60\u2009mm. One-third (5\/15) of the patients were inside the Nellix instructions for use. Technical success rate was 93.3%. No perioperative complications existed, and 30-day mortality was 0%. Median follow-up was 35 (interquartile range: 11\u201337) months. Survival rates at 1 and 3\u2009years were 80% and 59.3%. Abdominal aortic aneurysm\u2013related mortality occurred in 3 of 15 cases. Freedom from rupture rates at 1 and 3\u2009years were 92.9% and 66%. Freedom from endoleak rates at 1 and 3\u2009years were 92.9% and 74.5%. Freedom from reintervention rates at 1 and 3\u2009years were 86.7% and 70.6%, with a dramatic drop to 37.1% at 4\u2009years of follow-up. Three open surgery conversions were needed. There were no statistically significant differences in results between patients treated inside and outside instructions for use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The endovascular aneurysm sealing has shown encouraging short-term results, but its safety and effectiveness during time is questionable, because this system still carries high rates of reintervention, conversions for type IA endoleaks, and secondary aneurysm ruptures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1457496920917267","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T07:09:57Z","timestamp":1589785797000},"page":"233-240","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Three-Year Results of the Nellix Endovascular Aneurysm Sealing System for Treatment of Abdominal Aortic Aneurysms in Frail Patients with Poor Anatomical Features"],"prefix":"10.1177","volume":"110","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7934-257X","authenticated-orcid":false,"given":"A.","family":"Sonetto","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland"},{"name":"Department of Vascular Surgery, DIMES, Azienda Policlinico S. Orsola-Malpighi, Alma Mater Studiorum\u2014University of Bologna, Bologna, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Laukontaus","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Vikatmaa","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Intensive care and Pain Medicine, Helsinki University Hospital, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Aho","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8814-0988","authenticated-orcid":false,"given":"M.","family":"Venermo","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,5,18]]},"reference":[{"key":"bibr1-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1007\/BF02015271"},{"issue":"11","key":"bibr2-1457496920917267","first-page":"123","volume":"137","author":"Volodos\u2019 NL","year":"1986","journal-title":"Vestn Khir Im I I Grek"},{"key":"bibr3-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042002"},{"key":"bibr4-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2003.12.019"},{"key":"bibr5-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.03.007"},{"key":"bibr6-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.09.009"},{"key":"bibr7-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1177\/1708538115605430"},{"key":"bibr8-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.03.031"},{"key":"bibr9-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1583\/08-2422.1"},{"key":"bibr10-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1177\/1526602816664365"},{"key":"bibr11-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.03.024"},{"key":"bibr12-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.09.024"},{"key":"bibr13-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.09.032"},{"key":"bibr14-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(03)00318-5"},{"key":"bibr15-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2016.04.001"},{"key":"bibr16-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.123763"},{"key":"bibr17-1457496920917267","doi-asserted-by":"publisher","DOI":"10.2147\/MDER.S155300"},{"key":"bibr18-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.06.031"},{"key":"bibr19-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1177\/1526602818766864"},{"key":"bibr20-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.12.062"},{"key":"bibr21-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.02.003"},{"key":"bibr22-1457496920917267","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.09.020"}],"container-title":["Scandinavian Journal of Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1457496920917267","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1457496920917267","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1457496920917267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:58:11Z","timestamp":1777697891000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1457496920917267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,18]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1177\/1457496920917267"],"URL":"https:\/\/doi.org\/10.1177\/1457496920917267","relation":{},"ISSN":["1457-4969","1799-7267"],"issn-type":[{"value":"1457-4969","type":"print"},{"value":"1799-7267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,18]]}}}