{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:13:16Z","timestamp":1787019196101,"version":"build-2736575974"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scand J Surg"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aims:<\/jats:title>\n                    <jats:p>Managing infrainguinal vascular graft infections (VGI) in bypass reconstruction is complex. Although an autologous vein is the preferred graft material, alternative conduits are required when autologous veins are unavailable. This study aimed to compare the efficacy of cryopreserved arterial homografts and biosynthetic glutaraldehydemodifiedovine collagen grafts (Omniflow II) for the treatment of infrainguinal VGI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The study was retrospective across two centers and included patients with infrainguinal VGI treated with cryopreserved arterial homografts or Omniflow II grafts between 2009 and 2019. Freedom from reinfection, primary patency rates, amputation-free survival, and overall survival were analyzed using 5-year Kaplan-Meier estimates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Overall, 63 patients with infrainguinal VGI were treated with either Omniflow II grafts (n\u2009=\u200934) or cryopreserved arterial homografts (n\u2009=\u200929). At 5\u2009years, freedom from reinfection was 97.1% for Omniflow II grafts and 93.1% for cryopreserved arterial homografts (p\u2009=\u2009.4). Primary patency was 50% for Omniflow II grafts and 55.2% for the cryopreserved arterial homografts (p\u2009=\u2009.5). Amputation-free survival was 52.9% for Omniflow II grafts and 55.2% for cryopreserved arterial homografts (p\u2009=\u2009.7). No graft degeneration or graft ruptures were observed during the follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study suggests that biosynthetic grafts are viable and accessible alternatives for traditional graft materials, offering similar efficacy and ease of use. Although autologous vein grafts remain the gold standard for VGI management, biosynthetic grafts may serve as a viable alternatives to cryopreserved arterial homografts in the treatment of infrainguinal VGIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14574969251320721","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T03:05:35Z","timestamp":1741835135000},"page":"248-257","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Outcomes of biosynthetic collagen prostheses with comparison to cryopreserved arterial homografts for bypass reconstruction in infrainguinal vascular graft infections"],"prefix":"10.1177","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7674-0337","authenticated-orcid":false,"given":"Matthaeus","family":"Zerdzitzki","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery University Medical Center Regensburg Franz-Josef Strau\u00df Allee 11 93051 Regensburg Bavaria Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Pfister","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilma","family":"Schierling","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Zeman","sequence":"additional","affiliation":[{"name":"Center for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingolf","family":"Toepel","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Barmherzige Br\u00fcder Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Steinbauer","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Barmherzige Br\u00fcder Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Betz","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, University Medical Center Regensburg, Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.09.049"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.08.006"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.10.016"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.10.111"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1708538113504399"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/17085381211025380"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2016.203"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.11.011"},{"key":"e_1_3_3_10_2","unstructured":"LeMaitre. 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