{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:20:27Z","timestamp":1787836827709,"version":"build-2784847793"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100008730","name":"kreftforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008730","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Vestre Viken Hospital Trust"},{"DOI":"10.13039\/100031365","name":"Oslo universitetssykehus HF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scand J Surg"],"published-print":{"date-parts":[[2026,9]]},"abstract":"\n Background and aims:<\/jats:title>\n \n The primary aim was to compare disease-free survival (DFS), overall survival (OS), and post relapse survival (PRS) in patients undergoing transplantation for colorectal liver metastases (CRLM) who achieved complete metabolic response (CMR) on pre-transplant [\n 18<\/jats:sup>\n F]FDG PET\/CT after chemotherapy, with patients presenting with low or high metabolic tumor volume (MTV).\n <\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n Pre-operative [\n 18<\/jats:sup>\n F]FDG PET\/CT and diagnostic CT scans from 45 patients included in the Secondary Cancer (SECA) 1 and 2 studies were evaluated. MTV was derived from the [\n 18<\/jats:sup>\n F]FDG PET\/CT, and patients with CMR (MTV\u2009=\u20090) were identified. Patients were stratified into three subgroups: MTV 0, MTV low, and MTV high. DFS, OS, and PRS were compared using the Kaplan\u2013Meier method and the log-rank test. Baseline characteristics and CT reassessment data were analyzed using the Mann\u2013Whitney U test for continuous variables and Fisher\u2032s exact test for categorical variables.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Thirteen patients with CMR had significantly longer DFS and OS than patients in the MTV high group (\n p<\/jats:italic>\n \u2009=\u20090.033 and 0.030), but significantly shorter DFS and OS than those in the MTV low group (\n p<\/jats:italic>\n \u2009=\u20090.042 and 0.018). PRS did not differ significantly between patients with CMR and those with low or high MTV (\n p<\/jats:italic>\n \u2009=\u20090.121 and 0.130). Imaging findings of extensive growth along the liver capsule and\/or possible tumor extension beyond the liver capsule on CT had significantly shorter OS (\n p<\/jats:italic>\n \u2009=\u20090.010 and <0.001), including after exclusion of the MTV high group (0.034 and <0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Patients with CMR on [\n 18<\/jats:sup>\n F]FDG PET\/CT after chemotherapy prior to liver transplantation for CRLM had intermediate DFS, OS, and PRS compared with patients with low and high MTV.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/14574969261438696","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:02:51Z","timestamp":1777896171000},"page":"264-272","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Survival of patients with complete metabolic response on [\n 18<\/sup>\n F]FDG PET\/CT after chemotherapy prior to transplantation for colorectal liver metastases"],"prefix":"10.1177","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0997-3647","authenticated-orcid":false,"given":"Nadide Mutlukoca","family":"Stern","sequence":"first","affiliation":[{"name":"Department of Radiology Vestre Viken Hospital Trust Drammen 3004 Norway"},{"name":"Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway Institute of Clinical Medicine, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svein","family":"Dueland","sequence":"additional","affiliation":[{"name":"Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e5l-Dag","family":"Line","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, University of Oslo, Oslo, Norway"},{"name":"Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2278-5203","authenticated-orcid":false,"given":"Trygve","family":"Syversveen","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Grut","sequence":"additional","affiliation":[{"name":"Department of Radiology, Vestre Viken Hospital Trust, Drammen, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(21)00219-3"},{"issue":"1","key":"e_1_3_2_3_2","first-page":"1567","article-title":"Is orthotopic liver transplantation a feasible treatment for secondary cancer of the liver?","volume":"23","author":"M\u00fchlbacher F","year":"1991","unstructured":"M\u00fchlbacher F, Huk I, Steininger R, et al: Is orthotopic liver transplantation a feasible treatment for secondary cancer of the liver? Transplant Proc 1991;23(1 Pt. 2):1567\u20131568.","journal-title":"Transplant Proc"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003404"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2023.2932"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2022.0300"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)01595-2"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-022-01796-8"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-017-3843-9"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.8800"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.122.264106"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-024-06866-9"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/rg.220122"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-023-06393-z"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0000000000005538"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v13.i9.1043"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2300-z"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.057307"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2016-0334"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020200109"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2019.01.023"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2017015164"},{"key":"e_1_3_2_23_2","article-title":"Growth rates of pulmonary metastases after liver transplantation for unresectable colorectal liver metastases","volume":"105","author":"Grut H","year":"2017","unstructured":"Grut H, Solberg S, Seierstad T, et al: Growth rates of pulmonary metastases after liver transplantation for unresectable colorectal liver metastases. 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