{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:10:32Z","timestamp":1788667832147,"version":"build-2803163510"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Centre of clinical research V\u00e4stmanland"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scand J Surg"],"abstract":"<jats:sec>\n                    <jats:title>Background and aims:<\/jats:title>\n                    <jats:p>To evaluate survival according to treatment strategy among nonagenarians diagnosed with colorectal cancer in Sweden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective population-based register study used data from the Swedish Colorectal Cancer Registry. All patients aged \u2a7e90\u2009years diagnosed with colorectal cancer in Sweden between 2010 and 2019 were included. Patient demographics, tumour characteristics, treatment data, and perioperative outcomes were analysed. Overall survival and relative survival were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 2055 nonagenarians with colorectal cancer were identified. The median age was 91 (range: 90\u2013106), and 1254 (61%) were women. Overall, 1026 patients (50%) underwent bowel resection, of whom 655 (64%) had elective surgery.<\/jats:p>\n                    <jats:p>\n                      Among patients undergoing bowel resection, 1- and 3-year overall survival rates were 71% and 37%, respectively. Relative survival was comparable to that of the general population matched for age, sex, and calendar year. Patients who underwent elective resection had significantly longer median survival than those undergoing emergency surgery (37 vs 22\u2009months,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Emergency resection was associated with higher 30- and 90-day mortality than elective resection (15% vs 4%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and 26% vs 5%;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001, respectively).\n                    <\/jats:p>\n                    <jats:p>\n                      In multivariable Cox regression analysis restricted to patients undergoing bowel resection, male sex (hazard ratio\u2009=\u20091.30; standard error\u2009=\u20090.08;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), emergency surgery (hazard ratio\u2009=\u20091.70; standard error\u2009=\u20090.09;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), advanced tumour stage (hazard ratio\u2009=\u20091.61; standard error\u2009=\u20090.05;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and higher American Society of Anaesthesiologists score (hazard ratio\u2009=\u20091.35; standard error\u2009=\u20090.06;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001) were independently associated with an increased risk of death.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Half of all nonagenarians diagnosed with colorectal cancer underwent bowel resection. Survival following resection was comparable to that expected in the age-matched general population, whereas emergency surgery was associated with substantially higher short-term mortality and poorer long-term survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14574969261481930","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:12:01Z","timestamp":1788509521000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Survival following colorectal cancer resection in nonagenarians: A Swedish nationwide population-based study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2947-1947","authenticated-orcid":false,"given":"Parisa G.","family":"M\u00f6rlin","sequence":"first","affiliation":[{"name":"Division of Surgery, Department of Clinical Sciences, Karolinska Institute, Danderyd Hospital, Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan C.","family":"Sifolahzadeh","sequence":"additional","affiliation":[{"name":"Department of Primary Healthcare, V\u00e4ster\u00e5s, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maziar","family":"Nikberg","sequence":"additional","affiliation":[{"name":"Department of Surgical Science, Uppsala University, Sweden"},{"name":"Department of Surgery and Centre for Clinical Research, Region V\u00e4stmanland Hospital V\u00e4ster\u00e5s, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Matthiessen","sequence":"additional","affiliation":[{"name":"Department of Surgery, \u00d6rebro University Hospital, Sweden"},{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, \u00d6rebro University, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Chabok","sequence":"additional","affiliation":[{"name":"Division of Surgery, Department of Clinical Sciences, Karolinska Institute, Danderyd Hospital, Stockholm, Sweden"},{"name":"Department of Surgery and Centre for Clinical Research, Region V\u00e4stmanland Hospital V\u00e4ster\u00e5s, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Globocan\u2013global cancer observatory https:\/\/gco.iarc.fr\/en"},{"key":"e_1_3_3_3_2","unstructured":"Nationellt v\u00e5rdprogram tjock och \u00e4ndtarmscancer\u2013national care program for colorectalcancer https:\/\/kunskapsbanken.cancercentrum.se\/diagnoser\/tjock-och-andtarmscancer\/vardprogram\/"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1242458"},{"key":"e_1_3_3_5_2","unstructured":"Eurostat\u2013database\u2013life expectancy by age sex NUTS 2 region https:\/\/ec.europa.eu\/eurostat\/databrowser\/view\/demo_r_mlifexp\/default\/table?lang=en&category=demo.demomreg"},{"key":"e_1_3_3_6_2","unstructured":"World Health Organization. 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