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In order to study this topic, we used the infection evidence and the daily glycemic control data of 248 type-2 diabetics who participated in a large telemedicine study. The results showed that morning blood glucose was significantly elevated and that diabetics performed the measurements at a later time when infected. A simple model for predicting the occurrence of infection based on the glycemic control variables showed good performance (sensitivity: 56%, specificity: 92%). A set of variables that synthesize a diabetic\u2019s profile could be included in a dedicated model and facilitate the early detection of infections; other aspects, such as continuous self-monitoring and personalized medical records, should be examined in this direction. <\/jats:p>","DOI":"10.1177\/1460458211428427","type":"journal-article","created":{"date-parts":[[2012,3,24]],"date-time":"2012-03-24T06:49:43Z","timestamp":1332571783000},"page":"26-35","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Proof of concept for the role of glycemic control in the early detection of infections in diabetics"],"prefix":"10.1177","volume":"18","author":[{"given":"Taxiarchis","family":"Botsis","sequence":"first","affiliation":[{"name":"Columbia University, USA"},{"name":"University of Troms\u00f8, Norway"}]},{"given":"Albert M.","family":"Lai","sequence":"additional","affiliation":[{"name":"Columbia University, USA"}]},{"given":"Walter","family":"Palmas","sequence":"additional","affiliation":[{"name":"Columbia University, USA"}]},{"given":"Justin B.","family":"Starren","sequence":"additional","affiliation":[{"name":"Marshfield Clinic Research Foundation, USA"}]},{"given":"Gunnar","family":"Hartvigsen","sequence":"additional","affiliation":[{"name":"University of Troms\u00f8, Norway"}]},{"given":"George","family":"Hripcsak","sequence":"additional","affiliation":[{"name":"Columbia University, USA"}]}],"member":"179","published-online":{"date-parts":[[2012,3,23]]},"reference":[{"key":"bibr1-1460458211428427","unstructured":"Votey RS, Peters AL. 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