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Such inherent complexity has led to a challenge in developing decision support systems for epidemic information management, especially when data are from heterogeneous origins. In order to achieve a solution, an integrative framework is proposed. The Semantic Web is introduced in the context of enriching meaningful and machine-readable descriptions of epidemiological data. Software agents are utilised to achieve automation in semantic discovery, composition of data and process services. The objective is to enhance the performance in information retrieval in a dynamic decision-making environment while concealing technical complexity from inexperienced users. We illustrate how a prototype system can be developed by considering an epidemiology management scenario in which spatio-temporal analysis is undertaken of a specified epidemic.<\/jats:p>","DOI":"10.1177\/1460458213517704","type":"journal-article","created":{"date-parts":[[2014,1,21]],"date-time":"2014-01-21T22:28:46Z","timestamp":1390343326000},"page":"195-208","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["A multi-agent-based, semantic-driven system for decision support in epidemic management"],"prefix":"10.1177","volume":"21","author":[{"given":"Sen","family":"Li","sequence":"first","affiliation":[{"name":"Catholic University of Louvain, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William A","family":"Mackaness","sequence":"additional","affiliation":[{"name":"The University of Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,1,21]]},"reference":[{"key":"bibr1-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2005.03.009"},{"key":"bibr2-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1016\/j.compenvurbsys.2010.03.004"},{"key":"bibr3-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1177\/1010539511418819"},{"key":"bibr4-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1177\/1081180X08092829"},{"key":"bibr5-1460458213517704","first-page":"120","volume-title":"The 2nd international symposium on spatial data handling","author":"Armstrong MP","year":"1986"},{"key":"bibr6-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/02693799308901968"},{"key":"bibr7-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4571(199410)45:9<669::AID-ASI4>3.0.CO;2-P"},{"key":"bibr8-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/02693799608902088"},{"key":"bibr9-1460458213517704","volume-title":"Statistical methods in spatial epidemiology","author":"Lawson AB","year":"2001"},{"key":"bibr10-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-ento-120709-144847"},{"key":"bibr11-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2012.04.002"},{"key":"bibr12-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-9236(01)00137-3"},{"key":"bibr13-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/02693799608902085"},{"key":"bibr14-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/02693799308901941"},{"key":"bibr15-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/713811747"},{"key":"bibr16-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1186\/1742-7622-2-1"},{"key":"bibr17-1460458213517704","first-page":"869","volume":"14","author":"Li S","year":"2010","journal-title":"Chin J Dis Control Prev"},{"key":"bibr18-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1007\/b95170"},{"key":"bibr19-1460458213517704","volume-title":"The OpenGIS abstract specification","author":"Percivall G","year":"2002"},{"key":"bibr20-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1080\/13658810500287107"},{"key":"bibr21-1460458213517704","volume-title":"Proceedings of the AAAI fall symposium on semantic web and agents","author":"Klusch M","year":"2005"},{"key":"bibr22-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1016\/j.eswa.2008.01.037"},{"key":"bibr23-1460458213517704","first-page":"421","volume":"25","author":"Laclavik M","year":"2012","journal-title":"Comput Informat"},{"key":"bibr24-1460458213517704","doi-asserted-by":"publisher","DOI":"10.1007\/s10707-006-7635-9"},{"key":"bibr25-1460458213517704","volume-title":"Providing automated semantic support for software agents in spatial decision support systems","author":"Li S","year":"2008"},{"key":"bibr26-1460458213517704","unstructured":"McGuinness DL, Van Harmelen F. 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