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A computerized search of 16 databases of abstracts (e.g. Biomedical Reference Collection, Cochrane Central Register of Controlled Trials, Computers &amp; Applied Sciences Complete, Health Technology Assessments, MEDLINE) were explored in a systematic fashion to assess the presence of eHealth applications targeting health literacy. Compared to control interventions, the interventions using technology reported significant outcomes or showed promise for future positive outcomes regarding health literacy in a variety of settings, for different diseases, and with diverse samples. This review has indicated that it is feasible to deliver eHealth interventions specifically designed to improve health literacy skills for people with different health conditions, risk factors, and socioeconomic backgrounds. <\/jats:p>","DOI":"10.1177\/1460458214534092","type":"journal-article","created":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T04:49:18Z","timestamp":1402462158000},"page":"81-98","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":216,"title":["A systematic review of eHealth interventions to improve health literacy"],"prefix":"10.1177","volume":"22","author":[{"given":"Robin J","family":"Jacobs","sequence":"first","affiliation":[{"name":"Nova Southeastern University, USA"}]},{"given":"Jennie Q","family":"Lou","sequence":"additional","affiliation":[{"name":"Nova Southeastern University, USA"}]},{"given":"Raymond L","family":"Ownby","sequence":"additional","affiliation":[{"name":"Nova Southeastern University, USA"}]},{"given":"Joshua","family":"Caballero","sequence":"additional","affiliation":[{"name":"Nova Southeastern University, USA"}]}],"member":"179","published-online":{"date-parts":[[2014,6,10]]},"reference":[{"key":"bibr1-1460458214534092","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-2-201107190-00005"},{"key":"bibr2-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2007.07.022"},{"key":"bibr3-1460458214534092","volume-title":"Healthy people 2020: improving the health of Americans","author":"US Department of Health and Human Resources","year":"2013"},{"key":"bibr4-1460458214534092","volume-title":"National library of medicine current bibliographies in medicine: health literacy","author":"Ratzan SC","year":"2000"},{"key":"bibr5-1460458214534092","volume-title":"Literacy and health outcomes","author":"Berkman ND","year":"2004"},{"key":"bibr6-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2004.40153.x"},{"key":"bibr7-1460458214534092","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.87.6.1027"},{"key":"bibr8-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.1998.00242.x"},{"key":"bibr9-1460458214534092","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.92.8.1278"},{"key":"bibr10-1460458214534092","first-page":"A07","volume":"1","author":"Garbers S","year":"2004","journal-title":"Prev Chronic Dis"},{"key":"bibr11-1460458214534092","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.12.2980"},{"key":"bibr12-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.4.475"},{"key":"bibr13-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1497.2004.21130.x"},{"key":"bibr14-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.01.010"},{"key":"bibr15-1460458214534092","volume-title":"Literacy and health in America","author":"Rudd R","year":"2004"},{"key":"bibr16-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2006.08.006"},{"key":"bibr17-1460458214534092","first-page":"169","volume":"18","author":"Beer BB","year":"2003","journal-title":"J Gen Intern Med"},{"key":"bibr18-1460458214534092","unstructured":"United States Department of Health and Human Services, http:\/\/www.healthypeople.gov\/2020\/default.aspx (2010, accessed 22 November 2013)."},{"key":"bibr19-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1093\/heapro\/15.3.259"},{"key":"bibr20-1460458214534092","doi-asserted-by":"publisher","DOI":"10.17226\/10883"},{"key":"bibr21-1460458214534092","first-page":"169","volume-title":"Proceedings\/AMIA symposium","author":"Eysenbach G"},{"key":"bibr22-1460458214534092","volume-title":"Presented at the European Commission\u2019s first high-level conference on eHealth","author":"Silber D"},{"key":"bibr23-1460458214534092","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.8.1.e4"},{"key":"bibr24-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1177\/1938640007312299."},{"key":"bibr25-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1197\/jamia.M2744"},{"key":"bibr26-1460458214534092","doi-asserted-by":"publisher","DOI":"10.1177\/1524839908326380"},{"key":"bibr27-1460458214534092","unstructured":"Institute of Medicine (US) Roundtable on Health Literacy. 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