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There are a wide range of sepsis alerts in clinical care that act as clinical decision support tools to assist in early recognition of sepsis; however, there are serious shortcomings in existing health information technology for alerting providers in a meaningful way. Little work has been done to evaluate and assess existing alerts using implementation and process outcomes associated with health information technology displays, specifically evaluating clinician preference and performance. We developed graphical model displays of two popular sepsis scoring systems, quick Sepsis Related Organ Failure Assessment and Predisposition, Infection, Response, Organ Failure, using human factors principles grounded in user-centered and interaction design. Models will be evaluated in a larger research effort to optimize alert design to improve the collective awareness of high-risk populations and develop a relevant point-of-care clinical decision support system for sepsis.<\/jats:p>","DOI":"10.1177\/1460458219839623","type":"journal-article","created":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T07:59:28Z","timestamp":1557734368000},"page":"642-651","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Informatics and interaction: Applying human factors principles to optimize the design of clinical decision support for sepsis"],"prefix":"10.1177","volume":"26","author":[{"given":"Laura","family":"Schubel","sequence":"first","affiliation":[{"name":"MedStar Health, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle L","family":"Mosby","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital of Philadelphia, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Blumenthal","sequence":"additional","affiliation":[{"name":"MedStar Health, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muge","family":"Capan","sequence":"additional","affiliation":[{"name":"Drexel University\u2019s LeBow College of Business, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Arnold","sequence":"additional","affiliation":[{"name":"Drexel University College of Medicine, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Kowalski","sequence":"additional","affiliation":[{"name":"MedStar Health, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F Jacob","family":"Seagull","sequence":"additional","affiliation":[{"name":"University of Michigan, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Catchpole","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J Sanford","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Wharton, University of Pennsylvania, USA"},{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ella","family":"Franklin","sequence":"additional","affiliation":[{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin","family":"Littlejohn","sequence":"additional","affiliation":[{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8991-2342","authenticated-orcid":false,"given":"Kristen E","family":"Miller","sequence":"additional","affiliation":[{"name":"MedStar Health, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,5,13]]},"reference":[{"key":"bibr1-1460458219839623","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0288"},{"key":"bibr2-1460458219839623","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2012.03989.x"},{"key":"bibr3-1460458219839623","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31827c09f8"},{"key":"bibr4-1460458219839623","unstructured":"Torio C, Andrews R.\n                      National inpatient hospital costs: the most expensive conditions by payer, 2011\n                      . 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