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Based on 896 patients\u2019 data collected in Pakistan, we found that patients\u2019 adoption intention is a function of traveling cost, attitudes, and perceived usefulness. High traveling cost is found to have the most significant negative influence on adoption intention. Patients with shorter distance prefer more to use telemedicine. Traveling cost, traveling time, and traveling distance have indirect influences on adoption intention through their significant impacts on perceived usefulness and perceived ease of use. Our findings indicate that geographic locations does matter during promotion of telemedicine. 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