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Initially, only the financial domain benefited from Blockchain technologies. Due to efficient distribution format and data integrity security, however, these technologies have demonstrated potential in other areas, such as PHR data in the healthcare domain. Applying Blockchain to PHR data faces different challenges than applying it to financial transactions via crypto-currency. To propose and discuss an architectural model of a Blockchain platform named \u201cOmniPHR Multi-Blockchain\u201d to address key challenges associated with geographical distribution of PHR data. We analyzed the current literature to identify critical barriers faced when applying Blockchain technologies to distribute PHR data. We propose an architecture model and describe a prototype developed to evaluate and address these challenges. The OmniPHR Multi-Blockchain architecture yielded promising results for scenarios involving distributed PHR data. The project demonstrated a viable and beneficial alternative for processing geographically distributed PHR data with performance comparable with conventional methods. Blockchain\u2019s implementation tools have evolved, but the domain of healthcare still faces many challenges concerning distribution and interoperability. This study empirically demonstrates an alternative architecture that enables the distributed processing of PHR data via Blockchain technologies.<\/jats:p>","DOI":"10.1177\/14604582211007546","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T12:18:24Z","timestamp":1618489104000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Integrating multiple blockchains to support distributed personal health records"],"prefix":"10.1177","volume":"27","author":[{"given":"Alex","family":"Roehrs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3859-6199","authenticated-orcid":false,"given":"Cristiano A","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo R","family":"Righi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 H","family":"Mayer","sequence":"additional","affiliation":[{"name":"Universidade do Vale do Rio dos Sinos (UNISINOS), Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valter F","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 R","family":"Goldim","sequence":"additional","affiliation":[{"name":"Hospital de Cl\u00ednicas de Porto Alegre (HCPA), Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas C","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Vanderbilt University, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"bibr1-14604582211007546","author":"Nakamoto S.","year":"2008","journal-title":"Bitcoin: A peer-to-peer electronic cash system"},{"key":"bibr2-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnca.2019.02.027"},{"key":"bibr3-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocz214"},{"key":"bibr4-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1177\/1460458219866350"},{"key":"bibr5-14604582211007546","first-page":"25","volume-title":"2016 2nd International conference on open and big data (OBD)","author":"Azaria A"},{"key":"bibr6-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1177\/1460458218769699"},{"key":"bibr7-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-018-1121-4"},{"key":"bibr8-14604582211007546","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.5876"},{"key":"bibr9-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2020.105383"},{"key":"bibr10-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2020.105409"},{"key":"bibr11-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1109\/MCE.2017.2776459"},{"key":"bibr12-14604582211007546","volume":"170701873","author":"Cachin C","year":"2017","journal-title":"arXiv preprint arXiv"},{"key":"bibr13-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-018-0993-7"},{"key":"bibr14-14604582211007546","doi-asserted-by":"publisher","DOI":"10.2196\/12533"},{"key":"bibr15-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijinfomgt.2019.02.005"},{"key":"bibr16-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1007\/s10916-018-0997-3"},{"key":"bibr17-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2017.05.012"},{"key":"bibr18-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1109\/JBHI.2018.2836138"},{"key":"bibr19-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103140"},{"key":"bibr20-14604582211007546","doi-asserted-by":"publisher","DOI":"10.1109\/TNET.2002.808407"},{"key":"bibr21-14604582211007546","doi-asserted-by":"publisher","DOI":"10.2196\/13504"},{"key":"bibr22-14604582211007546","first-page":"18","volume":"16","author":"Szabo N.","year":"1996","journal-title":"EXTROPY J Transhumanist Thought"},{"key":"bibr23-14604582211007546","unstructured":"ISO. 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