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Methods: A literature review was performed using the PRISMA-ScR (2018) guidelines between Jan 2017 and June 2024 using the PubMed, ArXiv and semantic scholar databases. Results: Of the 694 records identified, 12 studies met the inclusion criteria. Although the role of eHealth interventions as well as telehealth in HIV management appears well established, there is a significant literature gap on the integration of telehealth and LLM technology. To address this, we provide a blueprint for the safe and ethical integration of LLM-TH into triage, history taking, patient education highlighting opportunities for reduced consultation time and improved quality of care. Conclusions: Variable access to mobile technology and the need for empirical validation stand out as limitations for LLM-TH. However, we argue that the current evidence base suggests the benefits far outweigh the challenges in applying LLM-TH for HIV care in Indonesia. We also argue this novel therapeutic modality is broadly applicable to the subacute general practice setting.<\/jats:p>","DOI":"10.1177\/14604582251315595","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T10:02:16Z","timestamp":1737194536000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["A blueprint for large language model-augmented telehealth for HIV mitigation in Indonesia: A scoping review of a novel therapeutic modality"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8987-3210","authenticated-orcid":false,"given":"Daniel","family":"Busch","sequence":"first","affiliation":[{"name":"Department of Computer Science and Information Technology, La Trobe University, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choiru","family":"Za\u2019in","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Information Technology, La Trobe University, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hei Man","family":"Chan","sequence":"additional","affiliation":[{"name":"School of Medicine, University of Queensland, Herston, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Haryanto","sequence":"additional","affiliation":[{"name":"Department of Human Centred Computing, Monash University, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wahyudi","family":"Agustiono","sequence":"additional","affiliation":[{"name":"Department of Information Systems, University of Trunojoyo Madura, Bangkalan, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kan","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Information Technology, La Trobe University, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyra","family":"Hamilton","sequence":"additional","affiliation":[{"name":"School of Applied Psychology, Griffith University, Southport, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7247-0894","authenticated-orcid":false,"given":"Jeroen","family":"Kroon","sequence":"additional","affiliation":[{"name":"School of Medicine and Dentistry, Griffith University, Southport, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Information Technology, La Trobe University, Melbourne, VIC, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,18]]},"reference":[{"key":"bibr1-14604582251315595","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-1595"},{"key":"bibr2-14604582251315595","unstructured":"UNAIDS. 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